UBE2J2 Antibody, Cy5 Conjugated

  • Catalog number
    bs-8381R-Cy5
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    UBE2J2 Polyclonal Antibody, Cy5 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Cy5
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    UBE2J2
  • Specificity
    This is a highly specific antibody against UBE2J2.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic peptide derived from human UBE2J2
  • Gene ID number
    118424
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    Ubiquitination is an important molecular mechanism by which abnormal or short-lived proteins are targeted for degradation by the concerted efforts of at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2J2 (Ubiquitin-conjugating enzyme E2 J2), also known as NCUBE2 (Non-canonical ubiquitin-conjugating enzyme 2), is a 259 amino acid single pass type IV membrane protein that that belongs to the E2 ubiquitin-conjugating enzyme family and is involved in protein degradation. Localized to the membrane of the endoplasmic reticulum (ER), UBE2J2 catalyzes the attachment of ubiquitin to misfolded membrane proteins, thereby targeting them for proteasomal destruction. This ATP-dependent reaction yields AMP, a diphosphate and a ubiquitin-tagged protein and may be a method of quality control within the ER. Two isoforms of UBE2J2 exist due to alternative splicing events.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    625,650nm/670nm
  • Synonyms
    NCUBE-2; NCUBE2; Non-canonical ubiquitin-conjugating enzyme 2; UB2J2_HUMAN; UBC6; UBC6 homolog; ube2j2; Ubiquitin-conjugating enzyme E2 J2.
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
  • Additional conjugation
    Cy5.5
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    UBE2J2
  • Short name
    Anti-UBE2J2
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    Cy5
  • Alternative name
    Anti-UBE2J2 PAb Cy5
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    ubiquitin conjugating enzyme E2 J2
  • Synonyms gene name
    • ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast)
    • ubiquitin-conjugating enzyme E2, J2
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2002-11-26
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Ubiquitin conjugating enzymes E2
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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