TUSC2 Antibody, Cy5 Conjugated

• Catalog number
  bs-5707R-Cy5
• Price
  Please ask
• Size
  0.1ml

• Long name
  TUSC2 Polyclonal Antibody, Cy5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  TUSC2
• Specificity
  This is a highly specific antibody against TUSC2.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human TUSC2
• Gene ID number
  11334
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  TUSC2/FUS1 is a novel tumor suppressor gene identified in the human chromosome 3p21.3 region where allele losses and genetic alterations occur early and frequently for many human cancers. Expression of TUSC2 protein is absent or reduced in the majority of lung cancers and premalignant lung lesions. Restoration of TUSC2 function in 3p21.3-deficient non-small cell lung carcinoma cells significantly inhibits tumor cell growth by induction of apoptosis and alteration of cell cycle kinetics. TUSC2 may induce apoptosis through the activation of the intrinsic mitochondrial-dependent and Apaf-1-associated pathways and inhibit the function of protein tyrosine kinases including EGFR, PDGFR, AKT, c-Abl, and c-Kit.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  625,650nm/670nm
• Synonyms
  C3orf11; FUS1; Fusion 1 protein; PAP; PDAP2; PDGFA associated protein 2; Tumor suppressor candidate 2; TUSC 2; TUSC2_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5
• French translation
  anticorps

• Gene target
  TUSC2   Conjugated  
• Gene symbol
  TUSC2
• Short name
  Anti-TUSC2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5
• Alternative name
  Anti-TUSC2 PAb Cy5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17034
• Gene
  TUSC2
• Long gene name
  tumor suppressor 2, mitochondrial calcium regulator
• Synonyms gene
  • PDAP2
• Synonyms gene name
  • PDGFA associated protein 2
  • tumor suppressor candidate 2
• Synonyms
  • FUS1
  • PAP
  • C3orf11
• GenBank acession
  • AF055479
• Locus
  3p21.31
• Discovery year
  2003-09-25
• Entrez gene record
  11334
• Pubmed identfication
  • 8780057
  • 11593436
• RefSeq identity
  • NM_007275
• VEGA ID
  OTTHUMG00000156877

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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