TSPAN12 Antibody, Cy5 Conjugated

• Catalog number
  bs-10425R-Cy5
• Price
  Please ask
• Size
  0.1ml

• Long name
  TSPAN12 Polyclonal Antibody, Cy5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  TSPAN12
• Specificity
  This is a highly specific antibody against TSPAN12.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  34-50/305
• Subcellular location
  Extracellular
• Source
  KLH conjugated synthetic peptide derived from human TSPAN12
• Gene ID number
  23554
• Swiss Prot
  O95859
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Regulator of cell surface receptor signal transduction. Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, while it does not activate the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1) (By similarity). Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP. Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP). Activates MMP14/MT1-MMP-dependent cleavage activity.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  625,650nm/670nm
• Synonyms
  EVR5; NET2; NET-2; TM4SF12; Tetraspanin-12; Tspan-12; Tetraspan NET-2; Transmembrane 4 superfamily member 12; TSPAN12; UNQ774/PRO1568
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5
• French translation
  anticorps

• Gene target
  TSPAN12   Conjugated  
• Gene symbol
  LINC02476, TSPAN12
• Short name
  Anti-TSPAN12
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5
• Alternative name
  Anti-TSPAN12 PAb Cy5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:53419
• Gene
  LINC02476
• Long gene name
  long intergenic non-protein coding RNA 2476
• Synonyms
  • LVCAT5
  • lnc-TSPAN12
• Synonyms name
  • liver cancer-associated transcript 5
• Locus
  7q31.31
• Discovery year
  2017-03-29
• Entrez gene record
  105375475
• Pubmed identfication
  • 32222644
• RefSeq identity
  • NR_131962
• Classification
  • Long intergenic non-protein coding RNAs

Gene info

• Identity
  HGNC:21641
• Gene
  TSPAN12
• Long gene name
  tetraspanin 12
• Synonyms gene
  • TM4SF12
• Synonyms gene name
  • transmembrane 4 superfamily member 12
• Synonyms
  • NET-2
• GenBank acession
  • AF124522
• Locus
  7q31.31
• Discovery year
  2003-07-21
• Entrez gene record
  23554
• RefSeq identity
  • NM_012338
• Classification
  • Tetraspanins
• VEGA ID
  OTTHUMG00000156980

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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