TAZ Antibody, Cy7 Conjugated
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Catalog numberbs-12367R-Cy7
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PricePlease ask
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Size0.1ml
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Long nameTAZ Polyclonal Antibody, Cy7 Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationCy7
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenTAZ
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SpecificityThis is a highly specific antibody against TAZ.
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ModificationUnmodified
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Modification siteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Immunogen_range15-70/400
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Subcellular locationCytoplasm, Nucleus
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SourceKLH conjugated synthetic peptide derived from human TAZ
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Gene ID number25937
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Swiss ProtQ9GZV5
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen backgroundTranscriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation. Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex. Regulates embryonic stem-cell self-renewal, promotes cell proliferation and epithelial-mesenchymal transition.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission743nm/767nm
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SynonymsTAZ; WW domain-containing transcription regulator protein 1; Transcriptional coactivator with PDZ-binding motif; WWTR1
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
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Additional conjugationCy7
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French translationanticorps
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Gene target
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Gene symbolWWTR1, ZBTB18, TAFAZZIN
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Short nameAnti-TAZ
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TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
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IsotypeImmunoglobulin G (IgG)
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LabelCy7
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Alternative nameAnti-TAZ PAb Cy7
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameWW domain containing transcription regulator 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-12-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namezinc finger and BTB domain containing 18
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Synonyms gene
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Synonyms gene name
- zinc finger protein 238
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-11-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BTB domain containing
- Zinc fingers C2H2-type
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametafazzin, phospholipid-lysophospholipid transacylase
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Synonyms gene
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Synonyms gene name
- endocardial fibroelastosis 2
- cardiomyopathy, dilated 3A (X-linked)
- tafazzin
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1989-05-29
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Entrez gene record
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Pubmed identfication
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data