SYT6(Thr418) Antibody, FITC Conjugated
-
Catalog number
bs-5636R-FITC
-
Price
Please ask
-
Size
0.1ml
-
-
Long name
SYT6(Thr418) Polyclonal Antibody, FITC Conjugated
-
Category
Conjugated Primary Antibodies
-
Conjugation
FITC
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
SYT6 Thr418
-
Specificity
This is a highly specific antibody against SYT6 Thr418.
-
Modification
Phosphorylation
-
Modification site
Thr418
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Source
KLH conjugated synthetic phosphopeptide derived from human SYT6 around the phosphorylation site of Thr418
-
Gene ID number
148281
-
Tested applications
IF(IHC-P)
-
Recommended dilutions
IF(IHC-P)(1:50-200)
-
Crossreactivity
Human, Mouse, Rat
-
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Antigen background
Synaptotagmins (Syts) are a large gene family of synaptic vesicle integral membrane proteins. Syt functions as regulators of both exocytosis /endocytosis and is involved in neurotransmitter secretion from small secretory vesicles. 13 isoforms of Syt have been identified(SytI-XIII). SynaptotagminVI is localized to the endoplasmic reticulum and/or Golgi like perinuclear compartment. It may be important for trafficking and calcium signaling as it is specially expressed in nonneuronal tissues. Also SytVI is present in the acrosomal region of mammalian spermatozoa. The cytosolic domain of SytVI can abrogate exocytosis by competing with the endogenous protein for essential interactions with the fusion machinery involved in a acrosomal exocytosis.
-
Purification method
This antibody was purified via Protein A.
-
Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
-
Excitation Emission
494nm/518nm
-
Synonyms
SYT6phospho T418; Synaptotagmin 6; Synaptotagmin VI; Synaptotagmin-6; Synaptotagmin6; SynaptotagminVI; Syt 6; Syt VI; Syt6; SYT6_HUMAN; SytVI.
-
Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
-
Additional conjugation
Anti-FITC Antibody
-
French translation
anticorps
-
Gene target
-
Gene symbol
SYT6
-
Short name
Anti-SYT6 Thr418
-
Technique
Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
-
Isotype
Immunoglobulin G (IgG)
-
Label
FITC
-
Alternative name
Anti-SYT6 Thr418 PAb FITC
-
Alternative technique
antibodies, fluorescine
-
Gene info
-
Identity
-
Gene
-
Long gene name
synaptotagmin 6
-
Synonyms gene name
-
Locus
-
Discovery year
2002-05-14
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
MeSH Data
-
Name
-
Concept
Scope note:
A method for the study of certain organic compounds within cells, in situ, by measuring the light intensities of the selectively stained areas of cytoplasm. The compounds studied and their locations in the cells are made to fluoresce and are observed under a microscope.
-
Tree numbers
- E01.370.225.500.386
- E05.196.712.516.600.240
- E05.200.500.386
- E05.242.386
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products