SP1 Antibody, FITC Conjugated

• Catalog number
  bs-0975R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  SP1 Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  SP1
• Specificity
  This is a highly specific antibody against SP1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  700-750/785
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic peptide derived from human TSFP1/SP1
• Gene ID number
  6667
• Swiss Prot
  P08047
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression. Isoform 3 is a stronger activator of transcription than isoform 1. Positively regulates the transcription of the core clock component ARNTL/BMAL1.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  Transcription factor Sp1; SP1; TSFP1
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  SP1   Conjugated  
• Gene symbol
  SP1, PRSS55, ST14
• Short name
  Anti-SP1
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-SP1 PAb FITC
• Alternative technique
  antibodies, fluorescine

Gene info

• Identity
  HGNC:11205
• Gene
  SP1
• Long gene name
  Sp1 transcription factor
• Synonyms name
  • specificity protein 1
• GenBank acession
  • J03133
• Locus
  12q13.13
• Discovery year
  1991-06-04
• Entrez gene record
  6667
• Pubmed identfication
  • 1662663
• Classification
  • Sp transcription factors
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000170047

Gene info

• Identity
  HGNC:30824
• Gene
  PRSS55
• Long gene name
  serine protease 55
• Synonyms gene name
  • protease, serine 55
• Synonyms
  • T-SP1
  • UNQ9391
  • CT153
• GenBank acession
  • AY358867
• Locus
  8p23.1
• Discovery year
  2010-04-14
• Entrez gene record
  203074
• Pubmed identfication
  • 12975309
  • 18844450
• RefSeq identity
  • NM_198464
• Classification
  • Serine proteases
• VEGA ID
  OTTHUMG00000129345

Gene info

• Identity
  HGNC:11344
• Gene
  ST14
• Long gene name
  ST14 transmembrane serine protease matriptase
• Synonyms gene
  • PRSS14
• Synonyms gene name
  • suppression of tumorigenicity 14 (colon carcinoma)
  • suppression of tumorigenicity 14
• Synonyms
  • SNC19
  • HAI
  • MT-SP1
  • TMPRSS14
  • CAP3
• Synonyms name
  • epithin
  • matriptase
  • channel–activating protein 3
• GenBank acession
  • AF118224
• Locus
  11q24.3
• Discovery year
  1998-05-05
• Entrez gene record
  6768
• Pubmed identfication
  • 9925927
  • 10373424
• Classification
  • Type II transmembrane serine proteases
• VEGA ID
  OTTHUMG00000165768

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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