SNX2 Antibody, HRP Conjugated

• Catalog number
  bs-12249R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  SNX2 Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  SNX2
• Specificity
  This is a highly specific antibody against SNX2.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  145-195/519
• Subcellular location
  Membrane bound
• Source
  KLH conjugated synthetic peptide derived from human SNX2
• Gene ID number
  6643
• Swiss Prot
  O60749
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:16179610). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex (PubMed:17101778). The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity (PubMed:23085988). Required for retrograde endosome-to-TGN transport of TGN38 (PubMed:20138391). Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN (PubMed:20604901).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  TRG-9; Sorting nexin-2; Transformation-related gene 9 protein; SNX2; TRG9
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  SNX2   Conjugated  
• Gene symbol
  SNX2
• Short name
  Anti-SNX2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-SNX2 PAb HRP
• Alternative technique
  antibodies
• Alternative to gene target
  sorting nexin 2, TRG-9, SNX2 and IDBG-38906 and ENSG00000205302 and 6643, phosphatidylinositol binding, Cytoplasm, Snx2 and IDBG-146883 and ENSMUSG00000034484 and 67804, BT.26946 and IDBG-644960 and ENSBTAG00000025358 and 509769

Gene info

• Identity
  HGNC:11173
• Gene
  SNX2
• Long gene name
  sorting nexin 2
• GenBank acession
  • AF043453
• Locus
  5q23.2
• Discovery year
  1996-07-17
• Entrez gene record
  6643
• Pubmed identfication
  • 9819414
• RefSeq identity
  • NM_003100
• Classification
  • Sorting nexins
  • PX-BAR domain containing
• VEGA ID
  OTTHUMG00000163020

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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