RPS6KA1(Ser363) Antibody, FITC Conjugated

• Catalog number
  bs-5681R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  RPS6KA1(Ser363) Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  RPS6KA1 Ser363
• Specificity
  This is a highly specific antibody against RPS6KA1 Ser363.
• Modification
  Phosphorylation
• Modification site
  Ser363
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human RPS6KA1 around the phosphorylation site of Ser363
• Gene ID number
  6195
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  RPS6KA1phospho S363; p90 RSK1 ; p90rsk ; p90S6K ; pp90RSK1 ; Ribosomal protein S6 kinase 90kD 1 ; Ribosomal protein S6 kinase 90kD polypeptide 1 ; Ribosomal protein S6 kinase 90kDa polypeptide 1 ; Ribosomal protein S6 kinase alpha 1 ; Ribosomal protein S6 kinase polypeptide 1 ; Ribosomal S6 kinase 1 ; RPS6K1 alpha ; rps6ka ; Rps6ka1 ; RSK 1 ; RSK 1 p90 ; RSK ; RSK1 ; S6K alpha 1 ; 90 kDa ribosomal protein S6 kinase 1 ; dJ590P13.1 ribosomal protein S6 kinase, 90kD, polypeptide 1 ; dJ590P13.1 ; EC 2.7.11.1 ; HU 1 ; HU1 ; MAP kinase activated protein kinase 1a ; MAPKAP kinase 1A ; MAPKAPK1A ; MGC79981 ; Mitogen-activated protein kinase-activated protein kinase 1A; KS6A1_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  RPS6KA1   Ser363   Conjugated  
• Gene symbol
  RPS6KA1
• Short name
  Anti-RPS6KA1 Ser363
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-RPS6KA1 Ser363 PAb FITC
• Alternative technique
  antibodies, fluorescine
• Alternative to gene target
  ribosomal protein S6 kinase, 90kDa, polypeptide 1, HU-1 and MAPKAPK1A and RSK and RSK1, RPS6KA1 and IDBG-94680 and ENSG00000117676 and 6195, transferase activity, nuclei, Rps6ka1 and IDBG-195412 and ENSMUSG00000003644 and 20111, RPS6KA1 and IDBG-645125 and ENSBTAG00000014447 and 533908

Gene info

• Identity
  HGNC:10430
• Gene
  RPS6KA1
• Long gene name
  ribosomal protein S6 kinase A1
• Synonyms gene name
  • ribosomal protein S6 kinase, 90kD, polypeptide 1
• Synonyms
  • RSK1
  • HU-1
  • p90Rsk
  • MAPKAPK1
• GenBank acession
  • BC014966
• Locus
  1p36.11
• Discovery year
  1994-07-11
• Entrez gene record
  6195
• Pubmed identfication
  • 8141249
  • 11049854
• RefSeq identity
  • NM_002953
• Classification
  • AGC family kinases
  • MAPK activated protein kinases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000004003

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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