RFC1 Antibody, FITC Conjugated

• Catalog number
  bs-11304R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  RFC1 Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  RFC1
• Specificity
  This is a highly specific antibody against RFC1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  420-465/1148
• Subcellular location
  Nucleus
• Source
  KLH conjugated synthetic peptide derived from human RFC1
• Gene ID number
  5981
• Swiss Prot
  P35251
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA. Interacts with C-terminus of PCNA. 5' phosphate residue is required for binding of the N-terminal DNA-binding domain to duplex DNA, suggesting a role in recognition of non-primer template DNA structures during replication and/or repair.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  A1; RFC; PO-GA; RECC1; MHCBFB; RFC140; Replication factor C subunit 1; Activator 1 140 kDa subunit; A1 140 kDa subunit; Activator 1 large subunit; Activator 1 subunit 1; DNA-binding protein PO-GA; Replication factor C 140 kDa subunit; RF-C 140 kDa subunit; Replication factor C large subunit; RFC1
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  RFC1   Conjugated  
• Gene symbol
  SLC19A1, RFC1
• Short name
  Anti-RFC1
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-RFC1 PAb FITC
• Alternative technique
  antibodies, fluorescine

Gene info

• Identity
  HGNC:10937
• Gene
  SLC19A1
• Long gene name
  solute carrier family 19 member 1
• Synonyms gene name
  • solute carrier family 19 (folate transporter), member 1
• Synonyms
  • FOLT
  • RFC1
• Synonyms name
  • reduced folate carrier 1
  • Folate transporter 1
• GenBank acession
  • U15939
• Locus
  21q22.3
• Discovery year
  1995-05-01
• Entrez gene record
  6573
• Pubmed identfication
  • 9570943
• Classification
  • Solute carriers
  • Minor histocompatibility antigens
• VEGA ID
  OTTHUMG00000090397

Gene info

• Identity
  HGNC:9969
• Gene
  RFC1
• Long gene name
  replication factor C subunit 1
• Synonyms gene name
  • replication factor C (activator 1) 1 (145kD)
  • replication factor C (activator 1) 1, 145kDa
• Synonyms
  • A1
  • PO-GA
  • RFC140
  • MHCBFB
• GenBank acession
  • L23320
• Locus
  4p14
• Discovery year
  1994-10-14
• Entrez gene record
  5981
• Pubmed identfication
  • 8114700
• RefSeq identity
  • NM_002913
• Classification
  • AAA ATPases
• VEGA ID
  OTTHUMG00000099363

MeSH Data

• Name
  Cytophotometry
• Concept
  Scope note: A method for the study of certain organic compounds within cells, in situ, by measuring the light intensities of the selectively stained areas of cytoplasm. The compounds studied and their locations in the cells are made to fluoresce and are observed under a microscope.
• Tree numbers
  • E01.370.225.500.386
  • E05.196.712.516.600.240
  • E05.200.500.386
  • E05.242.386
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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