Reticulon 4 Antibody, Cy5.5 Conjugated
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Catalog number
bs-1315R-Cy5.5
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Price
Please ask
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Size
0.1ml
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Long name
Reticulon 4 Polyclonal Antibody, Cy5.5 Conjugated
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Category
Conjugated Primary Antibodies
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Conjugation
Cy5.5
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
Reticulon 4
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Specificity
This is a highly specific antibody against Reticulon 4. Based on the location of the target sequence this antibody will recognize all isoforms(Nogo-A, Nogo-B, and Nogo-C).
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Modification
Unmodified
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Modification site
None
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Immunogen_range
1115-1160/1162
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Subcellular location
Cytoplasm
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Source
KLH conjugated synthetic peptide derived from Mouse Reticulon 4
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Gene ID number
68585
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Swiss Prot
Q99P72
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen background
Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The reticulon protein is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Reticulon 4 regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. It regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex. May inhibit BACE1 activity and amyloid precursor protein processing.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission
675nm/694nm
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Synonyms
Reticulon-4; Rtn4; Neurite outgrowth inhibitor; Nogo protein; Foocen; Neuroendocrine-specific protein; NSP; euroendocrine-specific protein C homolog; RTN-x; Reticulon-5; RTN 4A; Nogo-A; RTN-xL; RTN 4B; ASY; Nogo-B; RTN-xS; Foocen-M; RTN 4C; Nogo-C; Foocen-S; RTN4-B2; Rtn-T
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Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
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Additional conjugation
Cy5.5, Cy5.5
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Conjugated
These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
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French translation
anticorps
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Gene target
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Short name
Anti-Reticulon 4
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Technique
Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
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Isotype
Immunoglobulin G (IgG)
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Label
Cy5.5
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Alternative name
Anti-Reticulon 4 PAb Cy5.5
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Alternative technique
antibodies
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MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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