RAPGEF2/PDZ-GEF1 Antibody, Cy5.5 Conjugated
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Catalog numberbs-11581R-Cy5.5
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PricePlease ask
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Size0.1ml
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Long nameRAPGEF2/PDZ-GEF1 Polyclonal Antibody, Cy5.5 Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationCy5.5
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenRAPGEF2/PDZ-GEF1
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SpecificityThis is a highly specific antibody against RAPGEF2/PDZ-GEF1.
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ModificationUnmodified
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Modification siteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic peptide derived from human RAPGEF2
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen backgroundPDZ-GEF1 is a 1,499 amino acid cell membrane protein that functions as a guanine nucleotide exchange factor for Rap 1A, Rap 1B and Rap 2B GTPases. Expressed at highest levels in brain, PDZ-GEF1 is found at low levels in placenta, heart, lung and kidney, and undergoes post-translational phosphorylation following DNA damage. PDZ-GEF1 interacts with MAGI-2 and contains one Ras-GEF domain, a Ras-associating domain, one PDZ (DHR) domain, a single N-terminal Ras-GEF domain and a cyclic nucleotide-binding domain. The gene encoding PDZ-GEF1 maps to human chromosome 4q32.1.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission675nm/694nm
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SynonymsKIAA0313; Neural RAP guanine nucleotide exchange protein; nRap GEP; NRAPGEP; PDZ domain containing guanine nucleotide exchange factor 1; PDZ domain-containing guanine nucleotide exchange factor 1; PDZ GEF1; PDZ-GEF1; PDZGEF1; RA GEF; RA-GEF; Rap guanine nucleotide exchange factor 2; Rapgef2; RPGF2_HUMAN.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
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Additional conjugationCy5.5, Cy5.5
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ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694Â nm wavelengths.
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French translationanticorps
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Gene target
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Gene symbolRAPGEF2, ARHGEF11, RGS3, RAPGEF6, USH1C
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Short nameAnti-RAPGEF2/PDZ-GEF1
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TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
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IsotypeImmunoglobulin G (IgG)
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LabelCy5.5
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Alternative nameAnti-RAPGEF2/PDZ-GEF1 PAb Cy5.5
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameRap guanine nucleotide exchange factor 2
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Synonyms gene
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Synonyms gene name
- PDZ domain containing guanine nucleotide exchange factor (GEF) 1
- Rap guanine nucleotide exchange factor (GEF) 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-05-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
- PDZ domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRho guanine nucleotide exchange factor 11
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Synonyms gene name
- Rho guanine nucleotide exchange factor (GEF) 11
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-02-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PDZ domain containing
- Dbl family Rho GEFs
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameregulator of G protein signaling 3
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Synonyms gene name
- regulator of G-protein signalling 3
- regulator of G-protein signaling 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-06-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Regulators of G-protein signaling
- C2 domain containing
- PDZ domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameRap guanine nucleotide exchange factor 6
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Synonyms gene
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Synonyms gene name
- PDZ domain containing guanine nucleotide exchange factor (GEF) 2
- Rap guanine nucleotide exchange factor (GEF) 6
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-09-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PDZ domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameUSH1 protein network component harmonin
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Synonyms gene
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Synonyms gene name
- deafness, autosomal recessive 18
- Usher syndrome 1C (autosomal recessive, severe)
- Usher syndrome 1C
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1992-06-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PDZ domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
