PSCDBP/CYTIP Antibody, HRP Conjugated
-
Catalog number
bs-11062R-HRP
-
Price
Please ask
-
Size
0.1ml
-
-
Long name
PSCDBP/CYTIP Polyclonal Antibody, HRP Conjugated
-
Category
Conjugated Primary Antibodies
-
Conjugation
HRP
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
PSCDBP/CYTIP
-
Specificity
This is a highly specific antibody against PSCDBP/CYTIP.
-
Modification
Unmodified
-
Modification site
None
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Source
KLH conjugated synthetic peptide derived from human PSCDBP/CYTIP
-
Tested applications
WB, IHC-P
-
Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500)
-
Crossreactivity
Human, Mouse, Rat
-
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Antigen background
CYTIP is a cytoplasmic protein that is involved in lymphocytic cell adhesion. Expressed primarily in hematopoetic cells, CYTIP regulates the activity of cytohesin-1 (an integrin-activating protein involved in cell adhesion) by mediating its recruitment to the leukocyte membrane. Through its ability to bind cytohesin-1, CYTIP is able to sequester it to the cytoplasm, thereby preventing cytohesin-1 translocation to lymphocytes and interrupting the flow of information in the cell adhesion pathway. CYTIP can be recruited from the cytoplasm to the membrane by leukocyte integrins which interact with CYTIP through its PDZ domain. After membrane translocation, CYTIP can be re-located to the cytoplasm via exposure to a phorbol ester. Additionally, CYTIP associates with SNX27 (sorting nexin 27) and helps to coordinate trafficking and signaling complexes. Up-regulation of CYTIP is observed in maturing dendritic cells, suggesting a possible role in developmentally-controlled cell adhesion.
-
Purification method
This antibody was purified via Protein A.
-
Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
-
Excitation Emission
N/A
-
Synonyms
B31; CASP; Cbp HE; CYBR; CYTHIP; Cytip; CYTIP_HUMAN; Cytohesin binder and regulator; Cytohesin-associated scaffolding protein; Cytohesin-binding protein HE; Cytohesin-interacting protein; HE antibody Pleckstrin Homology Sec7 and Coiled-Coil Domains Binding Protein; Pleckstrin homology Sec7 and coiled-coil domains-binding protein.
-
Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
-
Additional conjugation
HRP Conjugated
-
French translation
anticorps
-
Gene target
-
Gene symbol
CYTIP
-
Short name
Anti-PSCDBP/CYTIP
-
Technique
Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
-
Isotype
Immunoglobulin G (IgG)
-
Label
HRP
-
Alternative name
Anti-PSCDBP/CYTIP PAb HRP
-
Alternative technique
antibodies
-
Alternative to gene target
cytohesin 1 interacting protein, B3-1 and CASP and CYBR and CYTHIP and HE and PSCDBP, CYTIP and IDBG-72874 and ENSG00000115165 and 9595, protein binding, nuclei, Cytip and IDBG-171958 and ENSMUSG00000026832 and 227929, CYTIP and IDBG-641611 and ENSBTAG00000008329 and 540450
-
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
