PRKCA(Thr637) Antibody, FITC Conjugated

• Catalog number
  bs-5574R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  PRKCA(Thr637) Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  PRKCA Thr637
• Specificity
  This is a highly specific antibody against PRKCA Thr637.
• Modification
  Phosphorylation
• Modification site
  Thr637
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human PRKCA around the phosphorylation site of Thr637
• Gene ID number
  5578
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  PRKCAphospho T637; rotein Kinase C; AAG6; Aging associated gene 6; MGC129900; MGC129901; MGC41878; MGC57564; PKC B; PKC beta; PKC zeta; PKC2; PKCB; PKCC; PKCD; PKCE; PKCG; PRKACA; PRKC A; PRKC G; PRKCA; PRKCB; PRKCB1; PRKCB2; PRKCD; PRKCE; PRKCG; PRKCZ ; Protein kinase C alpha; Protein kinase C alpha type; Protein Kinase C; Protein kinase C beta 1; Protein kinase C beta 1 polypeptide; Protein kinase C beta; Protein kinase C beta type; Protein kinase C delta; Protein kinase C epsilon; Protein kinase C gamma; Protein kinase C gamma type; Protein kinase C zeta; SCA14; Spinocerebellar ataxia 14.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  PRKCA   Thr637   Conjugated  
• Gene symbol
  PRKCA-AS1, PRKCA
• Short name
  Anti-PRKCA Thr637
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-PRKCA Thr637 PAb FITC
• Alternative technique
  antibodies, fluorescine
• Alternative to gene target
  protein kinase C, alpha, AAG6 and PKC-alpha and PKCA and PRKACA, PRKCA and IDBG-65194 and ENSG00000154229 and 5578, transferase activity, nuclei, Prkca and IDBG-213736 and ENSMUSG00000050965 and 18750, BT.62458 and IDBG-643753 and ENSBTAG00000001061 and 282001

Gene info

• Identity
  HGNC:51347
• Gene
  PRKCA-AS1
• Long gene name
  PRKCA antisense RNA 1
• GenBank acession
  • BC033554
• Locus
  17q24.2
• Discovery year
  2014-10-10
• Entrez gene record
  101928001
• RefSeq identity
  • NR_110822
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000179537

Gene info

• Identity
  HGNC:9393
• Gene
  PRKCA
• Long gene name
  protein kinase C alpha
• Synonyms gene
  • PKCA
• Synonyms gene name
  • protein kinase C, alpha
• Synonyms
  • PKCα
• Locus
  17q24.2
• Discovery year
  1991-08-02
• Entrez gene record
  5578
• Classification
  • C2 domain containing protein kinases
  • AGC family kinases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000179533

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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