PRAME Antibody, Biotin Conjugated

• Catalog number
  bs-7004R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  PRAME Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  PRAME
• Specificity
  This is a highly specific antibody against PRAME.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  180-227/509
• Subcellular location
  Nucleus, Cell membrane
• Source
  KLH conjugated synthetic peptide derived from human PRAME
• Gene ID number
  23532
• Swiss Prot
  P78395
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  MAPE; OIP4; CT130; OIP-4; Melanoma antigen preferentially expressed in tumors; Opa-interacting protein 4; Preferentially expressed antigen of melanoma; PRAME
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  PRAME   Conjugated  
• Gene symbol
  PRAME
• Short name
  Anti-PRAME
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-PRAME PAb Biotin
• Alternative technique
  antibodies
• Alternative to gene target
  preferentially expressed antigen in melanoma, CT130 and MAPE and OIP-4 and OIP4, PRAME and IDBG-2240 and ENSG00000185686 and 23532, retinoic acid receptor binding, nuclei

Gene info

• Identity
  HGNC:9336
• Gene
  PRAME
• Long gene name
  PRAME nuclear receptor transcriptional regulator
• Synonyms gene
  • MAPE
• Synonyms gene name
  • preferentially expressed antigen in melanoma
• Synonyms
  • CT130
• Synonyms name
  • cancer/testis antigen 130
• GenBank acession
  • U65011
• Locus
  22q11.22
• Discovery year
  1996-06-21
• Entrez gene record
  23532
• Pubmed identfication
  • 9047241
  • 10591208
• RefSeq identity
  • NM_206953
• Classification
  • PRAME family
• VEGA ID
  OTTHUMG00000151172

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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