PLCG2(Tyr1217) Antibody, Biotin Conjugated

• Catalog number
  bs-3338R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  PLCG2(Tyr1217) Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  PLCG2Tyr1217
• Specificity
  This is a highly specific antibody against PLCG2Tyr1217.
• Modification
  Phosphorylation
• Modification site
  Tyr1217
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human PLC gamma 2 around the phosphorylation site of Tyr1217
• Gene ID number
  5336
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water soluble phosphorylated derivatives of the lipid head groups. A number of these enzymes have specificity for phosphoinositides. Of the phosphoinositide specific phospholipase C enzymes, C beta is regulated by heterotrimeric G protein coupled receptors, while the closely related C gamma 1 and C gamma 2 enzymes are controlled by receptor tyrosine kinases. The C gamma 1 and C gamma 2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, SH2 and SH3.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  PLCG2phospho Y1217; PLC γ2Tyr1217; PLC gamma 2/PLCG2Tyr1217; PLC 2; PLC gamma 2; PLC IV; PLCG2; 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2; EC 3.1.4.11; Phosphoinositide phospholipase C; Phospholipase C gamma 2; Phospholipase C, gamma 2 phosphatidylinositol specic; PLCG2_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  PLCG2   Tyr1217   Conjugated  
• Gene symbol
  PLCG2
• Short name
  Anti-PLCG2Tyr1217
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-PLCG2Tyr1217 PAb Biotin
• Alternative technique
  antibodies
• Alternative to gene target
  phospholipase C, gamma 2 (phosphatidylinositol-specific), APLAID and FCAS3 and PLC-gamma-2 and PLC-IV, PLCG2 and IDBG-43723 and ENSG00000197943 and 5336, phosphoric diester hydrolase activity, Plasma membranes, Plcg2 and IDBG-195070 and ENSMUSG00000034330 and 234779, PLCG2 and IDBG-629513 and ENSBTAG00000002103 and 100337091

Gene info

• Identity
  HGNC:9066
• Gene
  PLCG2
• Long gene name
  phospholipase C gamma 2
• Synonyms gene name
  • phospholipase C, gamma 2 (phosphatidylinositol-specific)
• Locus
  16q24.1
• Discovery year
  1994-05-16
• Entrez gene record
  5336
• Pubmed identfication
  • 7835906
• Classification
  • C2 domain containing phospholipases
  • Phospholipases
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000176532
• Locus Specific Databases
  • LRG_376

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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