PLC beta3 (Ser537) Antibody, Cy5 Conjugated
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Catalog number
bs-3340R-Cy5
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Price
Please ask
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Size
0.1ml
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Long name
PLC beta3 (Ser537) Polyclonal Antibody, Cy5 Conjugated
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Category
Conjugated Primary Antibodies
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Conjugation
Cy5
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
PLC beta3 Ser537
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Specificity
This is a highly specific antibody against PLC beta3 Ser537.
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Modification
Phosphorylation
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Modification site
Ser537
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
KLH conjugated synthetic phosphopeptide derived from human PLC beta3 around the phosphorylation site of Ser537
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Gene ID number
5331
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen background
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission
625,650nm/670nm
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Synonyms
PLC beta3 Ser537; Phospholipase C beta 3; Phospholipase C beta 3 phosphatidylinositol specic; PLC beta 3; PLCB3 antibody 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase beta 3; Phosphoinositide phospholipase C; PLCB3_HUMAN.
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Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
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Additional conjugation
Cy5.5
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French translation
anticorps
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Gene target
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Gene symbol
PLCB1, PLCL1, PLCG1, PLCH2, PDIA3
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Short name
Anti-PLC beta3 Ser537
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Technique
Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
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Isotype
Immunoglobulin G (IgG)
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Label
Cy5
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Alternative name
Anti-PLC beta3 Ser537 PAb Cy5
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
phospholipase C beta 1
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Synonyms gene name
- phospholipase C, beta 1 (phosphoinositide-specific)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-06-21
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Entrez gene record
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Pubmed identfication
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Classification
- Phospholipases
- C2 domain containing phospholipases
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
phospholipase C gamma 1
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Synonyms gene
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Synonyms gene name
- phospholipase C, gamma 1 (formerly subtype 148)
- phospholipase C, gamma 1
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Synonyms
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GenBank acession
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Locus
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Discovery year
1989-05-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Pleckstrin homology domain containing
- MicroRNA protein coding host genes
- Phospholipases
- SH2 domain containing
- C2 domain containing phospholipases
- EF-hand domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
phospholipase C eta 2
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Synonyms gene
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Synonyms gene name
- phospholipase C-like 4
- phospholipase C, eta 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2004-07-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EF-hand domain containing
- Phospholipases
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VEGA ID
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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