PDGFRA(Tyr572)+PDGFRB(Tyr579) Antibody, Biotin Conjugated

• Catalog number
  bs-5533R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  PDGFRA(Tyr572)+PDGFRB(Tyr579) Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  PDGFRA Tyr572 + PDGFRB Tyr579
• Specificity
  This is a highly specific antibody against PDGFRA Tyr572 + PDGFRB Tyr579.
• Modification
  Phosphorylation
• Modification site
  Tyr579
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human PDGFRA around the phosphorylation site of Tyr572 [HE(p-Y)IY]
• Gene ID number
  5156
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  The PDGF Receptor Type A (Alpha platelet-derived growth factor receptor precursor, CD140a antigen), a 170kD protein, binds all three isoforms of PDGF with high affinity whereas the PDGF Receptor Type B, a 190kD protein, appears to bind only the PDGF BB homodimer with high affinity. Both receptors are transmembranous, ligand activated protein tyrosine kinases, which phosphorylate a number of important signal transduction proteins, which are bound with differential affinities via SH2 domains. The response of any given cell to PDGF will depend on the types of receptors displayed on the surface and isoforms of PDGF present in the extracellular environment.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  PDGFRAphospho Y572; PDGF Receptor alphaTyr849/PDGF Receptor beta Tyr857; Platelet–dirived growth factor receptor-alpha; Alpha platelet derived growth factor receptor; CD 140a; CD140a; CD140a antigen; MGC74795; PDGF alpha chain; PDGF R alpha; PDGFR 2; PDGFR A; PDGFR alpha; PDGFR2; PDGFRA; Platelet derived growth factor receptor 2; Platelet derived growth factor receptor alpha; Platelet derived growth factor receptor alpha polypeptide; PGFRA_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  PDGFRA   Tyr572   PDGFRB   Tyr579   Conjugated  
• Gene symbol
  PDGFRA, PDGFRB
• Short name
  Anti-PDGFRA Tyr572 + PDGFRB Tyr579
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-PDGFRA Tyr572 + PDGFRB Tyr579 PAb Biotin
• Alternative technique
  antibodies
• Alternative to gene target
  platelet-derived growth factor receptor, alpha polypeptide, CD140A and PDGFR-2 and PDGFR2 and RHEPDGFRA, PDGFRA and IDBG-18854 and ENSG00000134853 and 5156, transferase activity, nuclei, Pdgfra and IDBG-171929 and ENSMUSG00000029231 and 18595, PDGFRA and IDBG-642308 and ENSBTAG00000007173 and 282301

Gene info

• Identity
  HGNC:8803
• Gene
  PDGFRA
• Long gene name
  platelet derived growth factor receptor alpha
• Synonyms gene name
  • platelet-derived growth factor receptor, alpha polypeptide
• Synonyms
  • CD140a
  • PDGFR2
  • GAS9
• GenBank acession
  • D50001
• Locus
  4q12
• Discovery year
  1989-05-19
• Entrez gene record
  5156
• Pubmed identfication
  • 8643452
• RefSeq identity
  • NM_006206
• Classification
  • I-set domain containing
  • Receptor tyrosine kinases
  • CD molecules
• VEGA ID
  OTTHUMG00000128699
• Locus Specific Databases
  • LRG_309

Gene info

• Identity
  HGNC:8804
• Gene
  PDGFRB
• Long gene name
  platelet derived growth factor receptor beta
• Synonyms gene
  • PDGFR
• Synonyms gene name
  • platelet-derived growth factor receptor, beta polypeptide
• Synonyms
  • JTK12
  • CD140b
  • PDGFR1
• GenBank acession
  • M21616
• Locus
  5q32
• Discovery year
  2001-06-22
• Entrez gene record
  5159
• RefSeq identity
  • NM_002609
• Classification
  • Receptor tyrosine kinases
  • CD molecules
  • I-set domain containing
• VEGA ID
  OTTHUMG00000130053

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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