PABP (Methyl Arg455/460) Antibody, Cy5.5 Conjugated
-
Catalog number
bs-3836R-Cy5.5
-
Price
Please ask
-
Size
0.1ml
-
-
Long name
PABP (Methyl Arg455/460) Antibody, Cy5.5 Conjugated
-
Category
Conjugated Primary Antibodies
-
Conjugation
Cy5.5
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
PABP Methyl Arg455/460
-
Specificity
This is a highly specific antibody against PABP Methyl Arg455/460.
-
Modification
Methylation
-
Modification site
Methyl Arg455/460
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Immunogen_range
440-480/636
-
Subcellular location
Cytoplasm, Nucleus
-
Source
KLH conjugated synthetic metylpeptide derived from human PABP around metylation site of Arg455/Arg460
-
Gene ID number
26986
-
Swiss Prot
P11940
-
Tested applications
IF(IHC-P)
-
Recommended dilutions
IF(IHC-P)(1:50-200)
-
Crossreactivity
Human, Mouse, Rat
-
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Antigen background
Binds the poly(A) tail of mRNA, including that of its own transcript. May be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Involved in regulation of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons; for the recognition of premature termination codons (PTC) and initiation of NMD a competitive interaction between UPF1 and PABPC1 with the ribosome-bound release factors is proposed.
-
Purification method
This antibody was purified via Protein A.
-
Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
-
Excitation Emission
675nm/694nm
-
Synonyms
PAB1; PABP; PABP1; PABPC2; PABPL1; Polyadenylate-binding protein 1; PABP-1; Poly(A)-binding protein 1; PABPC1
-
Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
-
Additional conjugation
Cy5.5, Cy5.5
-
Conjugated
These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
-
Description
A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,
-
French translation
anticorps
-
Gene target
-
Short name
Anti-PABP Methyl Arg455/460
-
Technique
Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
-
Isotype
Immunoglobulin G (IgG)
-
Label
Cy5.5
-
Alternative name
Anti-PABP Methyl Arg455/460 PAb Cy5.5
-
Alternative technique
antibodies
-
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products