ODF2/Cenexin1 Antibody, HRP Conjugated

• Catalog number
  bs-10309R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  ODF2/Cenexin1 Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  ODF2/Cenexin1
• Specificity
  This is a highly specific antibody against ODF2/Cenexin1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Cytoplasm
• Source
  KLH conjugated synthetic peptide derived from human ODF2/Cenexin1
• Gene ID number
  4957
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Cenexin1 is an isoform of ODF2, that unlike ODF2 is present in several somatic cell types. Cenexin1 acts as a general scaffold protein that is specifically localised to the distal/subdistal appendages of mother centrioles. Cenexin1 is required for proper localization of Plk1 to the centrosomes. This centrosomal localization of Plk1 is required for proper microtubule function. Cenexin1 recruits Plk1 via a C-terminal extension of cenexin1 that is not present in ODF2. Cenexin1 is required for proper mitotic progression; depletion of Cenexin1 ultimately leads to chromosome missegregation and apoptosis. The ODF2 (outer dense fiber 2) gene encodes both ODF2 and Cenexin1, which have very different functions. ODF2 is a major component of sperm tail outer dense fibers (ODFs). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. They may help to maintain the passive elastic structures and elastic recoil of the sperm tail, and may also modulate sperm motility.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  sperm tail structural protein; 84 kDa outer dense fiber protein; Cenexin 1; Cenexin1 variant 1; KKT 4; KKT4; ODF 2; ODF 84; ODF2; ODF2/1; ODF2/2; ODF84; Outer dense fiber of sperm tail 2; Outer dense fiber of sperm tails 2; outer dense fiber of sperm tails; Outer dense fiber of sperm tails protein 2; Outer dense fiber of sperm tails, 84 kD; Outer dense fiber protein 2; Sperm outer dense fiber major protein 2; Testis specic autoantigen; ODFP2_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  ODF2/Cenexin1   Conjugated  
• Gene symbol
  ODF2-AS1, ODF2
• Short name
  Anti-ODF2/Cenexin1
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-ODF2/Cenexin1 PAb HRP
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:49461
• Gene
  ODF2-AS1
• Long gene name
  ODF2 antisense RNA 1
• GenBank acession
  • AW303426
• Locus
  9q34.11
• Discovery year
  2013-12-06
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000020745

Gene info

• Identity
  HGNC:8114
• Gene
  ODF2
• Long gene name
  outer dense fiber of sperm tails 2
• Synonyms gene name
  • outer dense fibre of sperm tails 2
• Synonyms
  • ODF84
  • CT134
• Synonyms name
  • cancer/testis antigen 134
  • cenexin
• GenBank acession
  • AF012549
• Locus
  9q34.11
• Discovery year
  1998-07-03
• Entrez gene record
  4957
• Pubmed identfication
  • 9045620
  • 10072582
• VEGA ID
  OTTHUMG00000020748

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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