MAPK8IP1 Antibody, FITC Conjugated

• Catalog number
  bs-6255R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  MAPK8IP1 Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  MAPK8IP1
• Specificity
  This is a highly specific antibody against MAPK8IP1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  435-485/711
• Subcellular location
  Cytoplasm
• Source
  KLH conjugated synthetic peptide derived from human JIP1/MAPK8IP1
• Gene ID number
  9479
• Swiss Prot
  Q9UQF2
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Required for JNK activation in response to excitotoxic stress. Cytoplasmic MAPK8IP1 causes inhibition of JNK-regulated activity by retaining JNK in the cytoplasm and inhibiting JNK phosphorylation of c-Jun. May also participate in ApoER2-specific reelin signaling. Directly, or indirectly, regulates GLUT2 gene expression and beta-cell function. Appears to have a role in cell signaling in mature and developing nerve terminals. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity). Functions as an anti-apoptotic protein and whose level seems to influence the beta-cell death or survival response.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  IB1; JIP1; JIP-1; PRKM8IP; C-Jun-amino-terminal kinase-interacting protein 1; JNK-interacting protein 1; Islet-brain 1; IB-1; JNK MAP kinase scaffold protein 1; Mitogen-activated protein kinase 8-interacting protein 1; MAPK8IP1
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  MAPK8IP1   Conjugated  
• Gene symbol
  MAPK8IP1
• Short name
  Anti-MAPK8IP1
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-MAPK8IP1 PAb FITC
• Alternative technique
  antibodies, fluorescine
• Alternative to gene target
  mitogen-activated protein kinase 8 interacting protein 1, IB1 and JIP-1 and JIP1 and PRKM8IP, MAPK8IP1 and IDBG-41200 and ENSG00000121653 and 9479, identical protein binding, nuclei, Mapk8ip1 and IDBG-192264 and ENSMUSG00000027223 and 19099, BT.105291 and IDBG-637017 and ENSBTAG00000000317 and 524806

Gene info

• Identity
  HGNC:6882
• Gene
  MAPK8IP1
• Long gene name
  mitogen-activated protein kinase 8 interacting protein 1
• Synonyms gene
  • PRKM8IP
• Synonyms
  • IB1
  • JIP-1
  • JIP1
• Locus
  11p11.2
• Discovery year
  1999-06-11
• Entrez gene record
  9479
• Pubmed identfication
  • 9235893
  • 9442013
• RefSeq identity
  • NM_005456
• VEGA ID
  OTTHUMG00000134324

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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