MAP3K4/MEK kinase-4 Antibody, FITC Conjugated

• Catalog number
  bs-11883R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  MAP3K4/MEK kinase-4 Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  MAP3K4/MEK kinase-4
• Specificity
  This is a highly specific antibody against MAP3K4/MEK kinase-4.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human MAP3K4/MEK kinase-4
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli including growth factors. The MEK kinases (also designated MAP kinase kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and p38. These activated MEKs in turn phosphorylate and activate the MAP kinases. The MEK kinases include Raf-1, Raf-B, Mos, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4, ASK 1 (MEK kinase-5) and MAP3K6 (MEK kinase-6). MEK kinase-1 has been shown to phosphorylate MEK-1 via Raf-independent pathway. Evidence suggests that MEK-3 is preferentially activated by MEK kinase-3 and that MEK-4 is activated by both MEK kinase-2 and MEK kinase-3. MEK kinase-4 has been shown to specifically activate the JNK path-way. ASK1 activates both MEK-4 and MEK-3/MEK-6 pathways.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  FLJ42439; KIAA0213; M3K4_HUMAN; MAP three kinase 1; MAP3K4; MAPK/ERK kinase kinase 4; MAPKKK4 antibodyMEK kinase 4; MEKK 4; MEKK4; Mitogen-activated protein kinase kinase kinase 4; MTK1; PRO0412; RP3-473J16.4
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  MAP3K4/MEK   kinase-4   Conjugated  
• Gene symbol
  MAP3K4-AS1, MAP3K4
• Short name
  Anti-MAP3K4/MEK kinase-4
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-MAP3K4/MEK kinase-4 PAb FITC
• Alternative technique
  antibodies, fluorescine
• Alternative to gene target
  mitogen-activated protein kinase kinase kinase 4, MAPKKK4 and MEKK 4 and MEKK4 and MTK1 and PRO0412, MAP3K4 and IDBG-98770 and ENSG00000085511 and 4216, transferase activity, Cytoplasm, Map3k4 and IDBG-136472 and ENSMUSG00000014426 and 26407, MAP3K4 and IDBG-635619 and ENSBTAG00000020079 and 511779

Gene info

• Identity
  HGNC:55048
• Gene
  MAP3K4-AS1
• Long gene name
  MAP3K4 antisense RNA 1
• GenBank acession
  • AK094629
• Locus
  6q26
• Discovery year
  2020-06-03
• Pubmed identfication
  • 32468015
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:6856
• Gene
  MAP3K4
• Long gene name
  mitogen-activated protein kinase kinase kinase 4
• Synonyms gene
  • MEKK4
• Synonyms
  • MTK1
  • MAPKKK4
  • KIAA0213
• GenBank acession
  • AF002715
• Locus
  6q26
• Discovery year
  1997-11-14
• Entrez gene record
  4216
• Pubmed identfication
  • 9305639
• Classification
  • Mitogen-activated protein kinase kinase kinases
• VEGA ID
  OTTHUMG00000015968

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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