MAP1A/MAP1B LC3 A/B Antibody, Cy7 Conjugated

• Catalog number
  bs-2912R-Cy7
• Price
  Please ask
• Size
  0.1ml

• Long name
  MAP1A/MAP1B LC3 A/B Antibody, Cy7 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy7
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  MAP1A/MAP1B LC3 A/B
• Specificity
  This is a highly specific antibody against MAP1A/MAP1B LC3 A/B.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  20-70/121
• Subcellular location
  Cytoplasm, Cell membrane
• Source
  KLH conjugated synthetic peptide derived from human MAP1A/MAP1B LC3 B
• Gene ID number
  81631, 84557
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, termed LC3-I and LC3-II, respectively. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  743nm/767nm
• Synonyms
  MAP LC3 beta; LC3; Autophagy related protein LC3 A; Autophagy related protein LC3 B; Autophagy related ubiquitin like modier LC3 A; Autophagy related ubiquitin like modier LC3 B; MAP1 light chain 3 like protein 1; MAP1 light chain 3 like protein 2; MAP1A/1B light chain 3 A; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 A; MAP1A/MAP1B LC3 B; MAP1ALC3; MAP1BLC3; MAP1LC3A; MAP1LC3B; Microtubule associated protein 1 light chain 3 alpha; Microtubule associated protein 1 light chain 3 beta; Microtubule associated proteins 1A/1B light chain 3; Microtubule associated proteins 1A/1B light chain 3A; Microtubule associated proteins 1A/1B light chain 3B.microtubule-associated proteins 1A/1B light chain 3 beta 2
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugated
  These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
• Additional conjugation
  Cy7
• French translation
  anticorps

• Gene target
  MAP1A/MAP1B   LC3   A/B   Conjugated  
• Gene symbol
  MAP1A, MAP1B, METAP1, MAP1LC3A
• Short name
  Anti-MAP1A/MAP1B LC3 A/B
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy7
• Alternative name
  Anti-MAP1A/MAP1B LC3 A/B PAb Cy7
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6835
• Gene
  MAP1A
• Long gene name
  microtubule associated protein 1A
• Synonyms gene
  • MAP1L
• GenBank acession
  • U38292
• Locus
  15q15.3
• Discovery year
  1992-07-09
• Entrez gene record
  4130
• Pubmed identfication
  • 7806212
  • 7629894
• RefSeq identity
  • NM_002373
• VEGA ID
  OTTHUMG00000059756

Gene info

• Identity
  HGNC:6836
• Gene
  MAP1B
• Long gene name
  microtubule associated protein 1B
• Synonyms
  • MAP5
  • PPP1R102
• Synonyms name
  • protein phosphatase 1, regulatory subunit 102
• GenBank acession
  • L06237
• Locus
  5q13.2
• Discovery year
  1992-02-06
• Entrez gene record
  4131
• Pubmed identfication
  • 1881920
• RefSeq identity
  • NM_005909
• Classification
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000100952

Gene info

• Identity
  HGNC:15789
• Gene
  METAP1
• Long gene name
  methionyl aminopeptidase 1
• Synonyms
  • KIAA0094
  • MetAP1A
  • MAP1A
• Synonyms name
  • Peptidase M
• GenBank acession
  • D42084
• Locus
  4q23
• Discovery year
  2001-09-26
• Entrez gene record
  23173
• Pubmed identfication
  • 7788527
  • 12144506
• RefSeq identity
  • NM_015143
• Classification
  • M24 metallopeptidase family
  • Aminopeptidases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000161231

Gene info

• Identity
  HGNC:6838
• Gene
  MAP1LC3A
• Long gene name
  microtubule associated protein 1 light chain 3 alpha
• Synonyms
  • MAP1BLC3
  • MAP1ALC3
  • LC3
  • LC3A
  • ATG8E
• Locus
  20q11.22
• Discovery year
  2000-06-29
• Entrez gene record
  84557
• Pubmed identfication
  • 8833088
  • 17580304
• RefSeq identity
  • NM_181509
• Classification
  • Autophagy related
• VEGA ID
  OTTHUMG00000032306

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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