LRP1(Ser4523) Antibody, Cy5.5 Conjugated

• Catalog number
  bs-5409R-Cy5.5
• Price
  Please ask
• Size
  0.1ml

• Long name
  LRP1(Ser4523) Polyclonal Antibody, Cy5.5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5.5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  LRP1 Ser4523
• Specificity
  This is a highly specific antibody against LRP1 Ser4523. This is the corresponding phosphorylation site in the following species: mouse ser(4524) rat ser(4524)
• Modification
  Phosphorylation
• Modification site
  Ser4523
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  4510-4525/4544
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic phosphopeptide derived from human LRP1 around the phosphorylation site of Ser4523
• Gene ID number
  4035
• Swiss Prot
  Q07954
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission. Functions as a receptor for Pseudomonas aeruginosa exotoxin A.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  675nm/694nm
• Synonyms
  APR; LRP; A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R; Prolow-density lipoprotein receptor-related protein 1; LRP-1; Alpha-2-macroglobulin receptor; Apolipoprotein E receptor; LRP1
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5, Cy5.5
• Conjugated
  These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
• French translation
  anticorps

• Gene target
  LRP1   Ser4523   Conjugated  
• Gene symbol
  LRP1-AS, C1D, LRP1
• Short name
  Anti-LRP1 Ser4523
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5.5
• Alternative name
  Anti-LRP1 Ser4523 PAb Cy5.5
• Alternative technique
  antibodies
• Alternative to gene target
  low density lipoprotein receptor-related protein 1, A2MR and APOER and APR and CD91 and IGFBP3R and LRP and LRP1A and TGFBR5, LRP1 and IDBG-42176 and ENSG00000123384 and 4035, lipoprotein particle receptor binding, nuclei, Lrp1 and IDBG-195360 and ENSMUSG00000040249 and 16971, LRP1 and IDBG-635332 and ENSBTAG00000010830 and 533894

Gene info

• Identity
  HGNC:51694
• Gene
  LRP1-AS
• Long gene name
  LRP1 antisense RNA
• Locus
  12q13.3
• Discovery year
  2015-05-07
• Entrez gene record
  105751187
• Pubmed identfication
  • 25937287
• RefSeq identity
  • NR_131938
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000171280

Gene info

• Identity
  HGNC:29911
• Gene
  C1D
• Long gene name
  C1D nuclear receptor corepressor
• Synonyms gene name
  • C1D nuclear receptor co-repressor
• Synonyms
  • SUNCOR
  • SUN-CoR
  • LRP1
  • Rrp47
• Synonyms name
  • small unique nuclear receptor co-repressor
• Locus
  2p14
• Discovery year
  2009-02-06
• Entrez gene record
  10438
• Pubmed identfication
  • 9469821
  • 17599775
  • 17412707
  • 11801738
  • 9405624
• RefSeq identity
  • NM_006333
• VEGA ID
  OTTHUMG00000129564

Gene info

• Identity
  HGNC:6692
• Gene
  LRP1
• Long gene name
  LDL receptor related protein 1
• Synonyms gene
  • APR
  • A2MR
• Synonyms gene name
  • alpha-2-macroglobulin receptor
  • low density lipoprotein receptor-related protein 1
• Synonyms
  • LRP
  • CD91
  • LRP1A
  • APOER
  • IGFBP3R1
  • IGFBP-3R
• Synonyms name
  • transforming growth factor-β receptor type V
• GenBank acession
  • X13916
• Locus
  12q13.3
• Discovery year
  1991-08-21
• Entrez gene record
  4035
• Pubmed identfication
  • 2548950
• RefSeq identity
  • NM_002332
• Classification
  • Low density lipoprotein receptors
  • CD molecules
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000044412

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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