LRP130 Antibody, Biotin Conjugated

• Catalog number
  bs-8719R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  LRP130 Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  LRP130
• Specificity
  This is a highly specific antibody against LRP130.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human LRP130
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Leucine-rich protein (LRP130) is a cytoplasmic mRNA-binding protein likely to be involved in the processing of mitochondrial DNA transcripts. Defects in the LRPPRC gene that encodes LRP130 result in the French-Canadian type of Leigh syndrome, a severe neurological disorder characterized by lesions in the subcortical region of the brain. LRP130 also interacts with the low-affinity receptor for leukemia inhibitory factor to produce an intracelluar signal cascade.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  LRPPRC; 130 kDa leucine-rich protein; GP130; Leucine-rich PPR-mot containing protein; LRP 130; LPPRC_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  LRP130   Conjugated  
• Gene symbol
  LRPPRC
• Short name
  Anti-LRP130
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-LRP130 PAb Biotin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:15714
• Gene
  LRPPRC
• Long gene name
  leucine rich pentatricopeptide repeat containing
• Synonyms gene
  • LSFC
• Synonyms gene name
  • Leigh syndrome, French-Canadian type (cytochrome oxidase deficiency)
• Synonyms
  • GP130
  • LRP130
• GenBank acession
  • M92439
• Locus
  2p21
• Discovery year
  2001-06-04
• Entrez gene record
  10128
• Pubmed identfication
  • 8012652
  • 8619474
  • 22045337
• RefSeq identity
  • NM_133259
• Classification
  • Mitochondrial respiratory chain complex assembly factors
  • Pentatricopeptide repeat containing
• VEGA ID
  OTTHUMG00000152782

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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