LAP2 alpha Antibody, HRP Conjugated
-
Catalog number
bs-13709R-HRP
-
Price
Please ask
-
Size
0.1ml
-
-
Long name
LAP2 alpha Polyclonal Antibody, HRP Conjugated
-
Category
Conjugated Primary Antibodies
-
Conjugation
HRP
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
LAP2 alpha
-
Specificity
This is a highly specific antibody against LAP2 alpha.
-
Modification
Unmodified
-
Modification site
None
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Source
KLH conjugated synthetic peptide derived from human LAP2
-
Tested applications
WB, IHC-P
-
Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500)
-
Crossreactivity
Human, Mouse, Rat
-
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Antigen background
The nuclear envelope separates the nucleoplasm from the cytoplasm in eukaryotic cells and includes the outer and inner nuclear membrane, nuclear pore complexes and the nuclear lamina. The nuclear lamina contains intermediate filament-type proteins called lamins that form a dense network to strengthen and stabilize the nuclear envelope. Lamina-associated polypeptide 2 (LAP2) is also known as thymopoietin. LAP2 is a nuclear envelope protein and contains an amino-terminal region called the LAP2-emerin-MAN1 or LEM motif. LAP2 also contains a unique DNA-binding amino-terminal domain. Alternative splicing produces six isoforms (α, β,γ, ε and δ) of mammalian LAP2 and three isoforms in Xenopus LAP2. LAP2α and LAP2β associate with chromosomal barrier-to-autointegration factor (BAF) and may play a role in stabilizing chromatin structure. LAP2β also binds to lamin B. LAP2α is a non-membrane isoform of LAP2 that associates with the internal nucleoskeleton and binds lamin A. The gene encoding human LAP2 maps to chromosome 12q23.1.
-
Purification method
This antibody was purified via Protein A.
-
Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
-
Excitation Emission
N/A
-
Synonyms
Isoforms beta/gamma; Lamina associated polypeptide 2 alpha; Lamina associated polypeptide 2; LAP2; Thymopoietin; Thymopoietin isoform alpha; TMPO; TP alpha; TP; LAP2 alpha; LAP2A_HUMAN.
-
Description
The Anti-LAP2 alpha is a α- or alpha protein sometimes glycoprotein present in blood.
-
Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
-
Additional conjugation
HRP Conjugated
-
French translation
anticorps
Gene info
Gene info
-
Identity
-
Gene
-
Long gene name
thymopoietin
-
Synonyms
-
Synonyms name
-
Locus
-
Discovery year
1994-11-08
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
-
Locus Specific Databases
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products