LAMP-1 Antibody, FITC Conjugated

• Catalog number
  bs-1970R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  LAMP-1 Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  LAMP-1
• Specificity
  This is a highly specific antibody against LAMP-1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  300-350/417
• Subcellular location
  Lumenal, Lysosome
• Source
  KLH conjugated synthetic peptide derived from human LAMP-1
• Gene ID number
  3916
• Swiss Prot
  P11279
• Tested applications
  FCM, IF(IHC-P)
• Recommended dilutions
  FCM(1:20-100), IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  LAMPA; CD17a; LGP12; Lysosome-associated membrane glycoprotein 1; LAMP-1; Lysosome-associated membrane protein 1; CD17 antigen-like family member A; LAMP1
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  LAMP-1   Conjugated  
• Gene symbol
  LAMP1, LAMP3, LSAMP, LAMP5, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1
• Short name
  Anti-LAMP-1
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-LAMP-1 PAb FITC
• Alternative technique
  antibodies, fluorescine

Gene info

• Identity
  HGNC:6499
• Gene
  LAMP1
• Long gene name
  lysosomal associated membrane protein 1
• Synonyms gene name
  • lysosomal-associated membrane protein 1
• Synonyms
  • CD107a
• GenBank acession
  • J03263
• Locus
  13q34
• Discovery year
  1990-07-15
• Entrez gene record
  3916
• Classification
  • Lysosome associated membrane proteins
  • CD molecules
• VEGA ID
  OTTHUMG00000017380

Gene info

• Identity
  HGNC:14582
• Gene
  LAMP3
• Long gene name
  lysosomal associated membrane protein 3
• Synonyms gene name
  • lysosomal-associated membrane protein 3
• Synonyms
  • LAMP
  • TSC403
  • DC-LAMP
  • DCLAMP
  • CD208
• GenBank acession
  • AB013924
• Locus
  3q27.1
• Discovery year
  2001-06-29
• Entrez gene record
  27074
• Pubmed identfication
  • 9721848
• Classification
  • Lysosome associated membrane proteins
  • CD molecules
• VEGA ID
  OTTHUMG00000158387

Gene info

• Identity
  HGNC:6705
• Gene
  LSAMP
• Long gene name
  limbic system associated membrane protein
• Synonyms gene name
  • limbic system-associated membrane protein
• Synonyms
  • LAMP
  • IGLON3
• Synonyms name
  • IgLON family member 3
• GenBank acession
  • U41901
• Locus
  3q13.31
• Discovery year
  1998-06-16
• Entrez gene record
  4045
• Pubmed identfication
  • 9615236
• RefSeq identity
  • NM_002338
• Classification
  • I-set domain containing
  • IgLON cell adhesion molecules
• VEGA ID
  OTTHUMG00000159308

Gene info

• Identity
  HGNC:16097
• Gene
  LAMP5
• Long gene name
  lysosomal associated membrane protein family member 5
• Synonyms gene
  • C20orf103
• Synonyms gene name
  • chromosome 20 open reading frame 103
  • lysosomal-associated membrane protein family, member 5
• Synonyms
  • dJ1119D9.3
  • BAD-LAMP
  • UNC-46
• Synonyms name
  • brain and dendritic cell associated LAMP
• GenBank acession
  • AL121740
• Locus
  20p12.2
• Discovery year
  2001-07-17
• Entrez gene record
  24141
• Pubmed identfication
  • 11780052
  • 21642595
• RefSeq identity
  • NM_012261
• Classification
  • Lysosome associated membrane proteins
• VEGA ID
  OTTHUMG00000031851

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:5760
• Gene
  IGKV1OR2-1
• Long gene name
  immunoglobulin kappa variable 1/OR2-1 (pseudogene)
• Synonyms gene
  • IGKVPZ1
  • IGKV1OR-1
• Synonyms gene name
  • immunoglobulin kappa variable 1/OR-1
  • immunoglobulin kappa variable 1/OR-1 pseudogene
  • immunoglobulin kappa variable 1/OR-1 (pseudogene)
• Synonyms
  • IGKV1/OR-1
  • IGKV1/OR2-1
• GenBank acession
  • Z12367
• Locus
  2p11.1
• Discovery year
  2000-04-18
• Entrez gene record
  3531
• Pubmed identfication
  • 2853098
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000155081

Gene info

• Identity
  HGNC:35281
• Gene
  MIR1289-1
• Long gene name
  microRNA 1289-1
• Synonyms gene
  • MIRN1289-1
• Synonyms
  • hsa-mir-1289-1
• Locus
  20q11.22
• Discovery year
  2008-11-03
• Entrez gene record
  100302125
• RefSeq identity
  • NR_031620
• Classification
  • MicroRNA MIR1289 family

MeSH Data

• Name
  Cytophotometry
• Concept
  Scope note: A method for the study of certain organic compounds within cells, in situ, by measuring the light intensities of the selectively stained areas of cytoplasm. The compounds studied and their locations in the cells are made to fluoresce and are observed under a microscope.
• Tree numbers
  • E01.370.225.500.386
  • E05.196.712.516.600.240
  • E05.200.500.386
  • E05.242.386
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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