KCNA2B/Kv beta 2 Antibody, Biotin Conjugated

• Catalog number
  bs-12182R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  KCNA2B/Kv beta 2 Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  KCNA2B/Kv beta 2
• Specificity
  This is a highly specific antibody against KCNA2B/Kv beta 2.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human KCNA2B/Kv beta 2
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution, and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming a-subunits (KV), which include the KV1, KV2, KV3, and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. Differences exist in the patterns of trafficking, biosynthetic processing, and surface expression of the major KV1 subunits (KV1.1, KV1.2, and KV1.4) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels. KV beta.2 can also be designated KCNAB2, KKv beta2.1 or AKR6A5.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  AKR6A5; HKv beta 2; HKvbeta 2; HKvbeta2.1; HKvbeta2.2; K+ channel subunit beta 2; K+ channel beta 2 subunit; KCNA2B; KCNAB 2; KCNAB2; KCNK2; Kv Beta 2; Kvbeta2; MGC117289; Potassium channel shaker chain beta 2; Potassium voltage gated channel shaker related subfamily; Potassium voltage gated channel shaker related subfamily beta member 2; Voltage gated potassium channel beta 2 subunit; Voltage gated potassium channel subunit beta 2;
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  KCNA2B/Kv   beta   Conjugated  
• Gene symbol
  KCNAB2
• Short name
  Anti-KCNA2B/Kv beta 2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-KCNA2B/Kv beta 2 PAb Biotin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6229
• Gene
  KCNAB2
• Long gene name
  potassium voltage-gated channel subfamily A regulatory beta subunit 2
• Synonyms gene name
  • potassium voltage-gated channel, shaker-related subfamily, beta member 2
  • potassium channel, voltage gated subfamily A regulatory beta subunit 2
• Synonyms
  • AKR6A5
  • KCNA2B
  • HKvbeta2.1
  • HKvbeta2.2
• GenBank acession
  • U33429
• Locus
  1p36.31
• Discovery year
  1998-10-13
• Entrez gene record
  8514
• Pubmed identfication
  • 8838324
• RefSeq identity
  • NM_172130
• Classification
  • Aldo-keto reductases
  • Potassium voltage-gated channel regulatory subunits
• VEGA ID
  OTTHUMG00000000795

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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