KALRN/Duo Antibody, Cy5.5 Conjugated

• Catalog number
  bs-11861R-Cy5.5
• Price
  Please ask
• Size
  0.1ml

• Long name
  KALRN/Duo Polyclonal Antibody, Cy5.5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5.5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  KALRN/Duo
• Specificity
  This is a highly specific antibody against KALRN/Duo.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human KALRN/Duo
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  HAP1 (huntingtin-associated protein 1) binds to huntingtin (1). Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington’s disease (HD) (2,3). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region (1). HAP1 shows neuronal localization and moves with huntingtin in nerve fibers (4,5). HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem (1). Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons (6). Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  675nm/694nm
• Synonyms
  Duo; FLJ16443; HAPIP; Huntingtin associated protein interacting protein duo ; Huntingtin-associated protein-interacting protein; Kalirin isoform 2; Kalirin; KALRN ; KALRN_HUMAN ; Protein Duo; RhoGEF kinase; Serine/threonine kinase with Dbl and pleckstrin homology domains ; Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain; TRAD.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5, Cy5.5
• Conjugated
  These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
• French translation
  anticorps

• Gene target
  KALRN/Duo   Conjugated  
• Gene symbol
  KALRN
• Short name
  Anti-KALRN/Duo
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5.5
• Alternative name
  Anti-KALRN/Duo PAb Cy5.5
• Alternative technique
  antibodies
• Alternative to gene target
  kalirin, RhoGEF kinase, ARHGEF24 and CHD5 and CHDS5 and DUET and DUO and HAPIP and TRAD, KALRN and IDBG-53661 and ENSG00000160145 and 8997, transferase activity, Cytoplasm, Kalrn and IDBG-155984 and ENSMUSG00000061751 and 545156, KALRN and IDBG-633466 and ENSBTAG00000002640 and 540675

Gene info

• Identity
  HGNC:4814
• Gene
  KALRN
• Long gene name
  kalirin RhoGEF kinase
• Synonyms gene
  • HAPIP
• Synonyms gene name
  • huntingtin-associated protein interacting protein (duo)
• Synonyms
  • duo
  • Hs.8004
  • TRAD
  • DUET
  • Kalirin
  • ARHGEF24
• Synonyms name
  • serine/threonine kinase with Dbl and pleckstrin homology domains
• GenBank acession
  • U94190
• Locus
  3q21.1-q21.2
• Discovery year
  1999-01-13
• Entrez gene record
  8997
• Pubmed identfication
  • 9285789
  • 10023074
• RefSeq identity
  • NM_003947
• Classification
  • I-set domain containing
  • Fibronectin type III domain containing
  • Dbl family Rho GEFs
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000125545

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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