IP3 Receptor Antibody, HRP Conjugated

• Catalog number
  bs-8869R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  IP3 Receptor Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  IP3 Receptor
• Specificity
  This is a highly specific antibody against IP3 Receptor.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  110-160/2758
• Subcellular location
  Cytoplasm
• Source
  KLH conjugated synthetic peptide derived from human IP3 Receptor
• Gene ID number
  3708
• Swiss Prot
  Q14643
• Tested applications
  IHC-P
• Recommended dilutions
  IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1; PPP1R94; Inositol 1,4,5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; Type 1 inositol 1,4,5-trisphosphate receptor; Type 1 InsP3 receptor; ITPR1
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  IP3   Receptor   Conjugated  
• Gene symbol
  ITPKB, ITPKA, ITPKC, CFAP61
• Short name
  Anti-IP3 Receptor
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-IP3 Receptor PAb HRP
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6179
• Gene
  ITPKB
• Long gene name
  inositol-trisphosphate 3-kinase B
• Synonyms gene name
  • inositol 1,4,5-trisphosphate 3-kinase B
• Synonyms
  • IP3KB
  • IP3-3KB
• GenBank acession
  • AJ242780
• Locus
  1q42.12
• Discovery year
  1992-04-15
• Entrez gene record
  3707
• Pubmed identfication
  • 1654894
  • 1330886
• RefSeq identity
  • NM_002221
• VEGA ID
  OTTHUMG00000037582

Gene info

• Identity
  HGNC:6178
• Gene
  ITPKA
• Long gene name
  inositol-trisphosphate 3-kinase A
• Synonyms gene name
  • inositol 1,4,5-trisphosphate 3-kinase A
• Synonyms
  • IP3KA
  • IP3-3KA
• GenBank acession
  • X54938
• Locus
  15q15.1
• Discovery year
  1992-04-15
• Entrez gene record
  3706
• Pubmed identfication
  • 1330886
  • 2175886
• RefSeq identity
  • NM_002220
• VEGA ID
  OTTHUMG00000130343

Gene info

• Identity
  HGNC:14897
• Gene
  ITPKC
• Long gene name
  inositol-trisphosphate 3-kinase C
• Synonyms gene name
  • inositol 1,4,5-trisphosphate 3-kinase C
• Synonyms
  • IP3KC
  • IP3-3KC
• GenBank acession
  • Y11999
• Locus
  19q13.2
• Discovery year
  2001-06-28
• Entrez gene record
  80271
• Pubmed identfication
  • 11085927
• RefSeq identity
  • NM_025194
• VEGA ID
  OTTHUMG00000182688

Gene info

• Identity
  HGNC:15872
• Gene
  CFAP61
• Long gene name
  cilia and flagella associated protein 61
• Synonyms gene
  • C20orf26
• Synonyms gene name
  • chromosome 20 open reading frame 26
• Synonyms
  • DKFZP434K156
  • dJ1002M8.3
  • CaM-IP3
• Synonyms name
  • hypothetical protein LOC26074
• GenBank acession
  • AL117439
• Locus
  20p11.23
• Discovery year
  2001-06-21
• Entrez gene record
  26074
• Pubmed identfication
  • 11780052
  • 17967944
• RefSeq identity
  • NM_015585
• Classification
  • Cilia and flagella associated
• VEGA ID
  OTTHUMG00000032006

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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