IKK gamma(Ser43) Antibody, Cy3 Conjugated
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Catalog numberbs-5393R-Cy3
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PricePlease ask
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Size0.1ml
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Long nameIKK gamma(Ser43) Polyclonal Antibody, Cy3 Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationCy3
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenIKK gamma Ser43
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SpecificityThis is a highly specific antibody against IKK gamma Ser43.
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ModificationPhosphorylation
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Modification siteSer43
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic phosphopeptide derived from human IKBKG around the phosphorylation site of Ser43
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Gene ID number8517
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen backgroundPro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission512,550nm/570,615nm
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SynonymsIkB kinase associated protein 1; IkB kinase subunit gamma; Inhibitor of nuclear factor kappa B kinase subunit gamma; AMCBX1; FIP 3; FIP3; Fip3p; I kappa B kinase gamma; IkB kinase associated protein 1; IkB kinase gamma subunit; IkB kinase subunit gamma; IKBKG; IKKAP 1; IKKAP1; IKKG; IKKgamma;IKK gamma.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the Anti-IKK gamma Ser43 can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy.
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Additional conjugationcy3 conjugation kit
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French translationanticorps
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Gene target
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Gene symbolIKBKE, IKBKB, CHUK, IKBKG
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Short nameAnti-IKK gamma Ser43
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TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
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IsotypeImmunoglobulin G (IgG)
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LabelCy3
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Alternative nameAnti-IKK gamma Ser43 PAb Cy3
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameinhibitor of nuclear factor kappa B kinase subunit epsilon
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Synonyms gene name
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-12-02
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Entrez gene record
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Pubmed identfication
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Classification
- I kappa B kinases
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinhibitor of nuclear factor kappa B kinase subunit beta
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Synonyms gene name
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-02-11
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Entrez gene record
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Pubmed identfication
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Classification
- I kappa B kinases
- IKK complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namecomponent of inhibitor of nuclear factor kappa B kinase complex
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Synonyms gene
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Synonyms gene name
- conserved helix-loop-helix ubiquitous kinase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-03-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- I kappa B kinases
- IKK complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameinhibitor of nuclear factor kappa B kinase regulatory subunit gamma
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Synonyms gene
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Synonyms gene name
- incontinentia pigmenti
- inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
- inhibitor of nuclear factor kappa B kinase subunit gamma
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-09-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers C2HC-type
- IKK complex
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
