IKB epsilon (Ser157) Antibody, Cy7 Conjugated
#
-
Catalog numberbs-5517R-Cy7
-
Price:
-
Size0.1ml
-
-
Long nameIKB epsilon (Ser157) Polyclonal Antibody, Cy7 Conjugated
-
CategoryConjugated Primary Antibodies
-
ConjugationCy7
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenIKB epsilon Ser157
-
SpecificityThis is a highly specific antibody against IKB epsilon Ser157.
-
ModificationPhosphorylation
-
Modification siteSer157
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
SourceKLH conjugated synthetic phosphopeptide derived from human NFKBIE around the phosphorylation site of Ser157
-
Gene ID number4794
-
Tested applicationsIF(IHC-P)
-
Recommended dilutionsIF(IHC-P)(1:50-200)
-
CrossreactivityHuman
-
Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Antigen backgroundNFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). For some genes, activation requires NFKB interaction with other transcription factors, such as STAT, AP1 (JUN), and NFAT.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
-
Excitation Emission743nm/767nm
-
SynonymsNFKBIE phospho S157; IKB epsilon Ser157; IKB epsilon S; p-IKB epsilon Ser157; p-IKB epsilon S157; I kappa B epsilon; IkappaBepsilon; IkB E; IKBE; IKB epsilon; MGC72568; NF kappa B inhibitor epsilon; NF kappa BIE; NFkappa BIE; NFkappaB inhibitor epsilon; NFKBIE; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor epsilon; OTTHUMP00000016522; Slc35b2; solute carrier family 35, member B2.
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
-
Additional conjugationCy7
-
French translationanticorps
-
Gene target
-
Short nameAnti-IKB epsilon Ser157
-
TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
-
IsotypeImmunoglobulin G (IgG)
-
LabelCy7
-
Alternative nameAnti-IKB epsilon Ser157 PAb Cy7
-
Alternative techniqueantibodies
-
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data