HSP90 alpha (Thr5 + Thr7) Antibody, FITC Conjugated

• Catalog number
  bs-3181R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  HSP90 alpha (Thr5 + Thr7) Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  HSP90 alpha Thr5 + Thr7
• Specificity
  This is a highly specific antibody against HSP90 alpha Thr5 + Thr7. These phosphorylation sites are homologous across the listed species.
• Modification
  Phosphorylation
• Modification site
  Thr5 + Thr7
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  1-50/732
• Subcellular location
  Cytoplasm, Cell membrane
• Source
  KLH conjugated synthetic phosphopeptide derived from human HSP90 around the phosphorylation site of Thr5/7
• Gene ID number
  3320
• Swiss Prot
  P07900
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4; Heat shock protein HSP 90-alpha; Heat shock 86 kDa; HSP 86; Lipopolysaccharide-associated protein 2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38; HSP90AA1
• Description
  The Anti-HSP90 alpha Thr5 + Thr7 is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  HSP90   alpha   Thr5   Thr7   Conjugated  
• Gene symbol
  HSP90AA1
• Short name
  Anti-HSP90 alpha Thr5 + Thr7
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-HSP90 alpha Thr5 + Thr7 PAb FITC
• Alternative technique
  antibodies, fluorescine

Gene info

• Identity
  HGNC:5253
• Gene
  HSP90AA1
• Long gene name
  heat shock protein 90 alpha family class A member 1
• Synonyms gene
  • HSPC1
  • HSPCA
• Synonyms gene name
  • heat shock 90kD protein 1, alpha
  • heat shock 90kDa protein 1, alpha
  • heat shock protein 90kDa alpha (cytosolic), class A member 1
• Synonyms
  • Hsp89
  • Hsp90
  • FLJ31884
  • HSP90N
• GenBank acession
  • M27024
• Locus
  14q32.31
• Discovery year
  1990-06-27
• Entrez gene record
  3320
• Pubmed identfication
  • 2527334
  • 16269234
• RefSeq identity
  • NM_005348
• Classification
  • Heat shock 90kDa proteins
• VEGA ID
  OTTHUMG00000171752

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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