HP1(Tyr43) Antibody, FITC Conjugated
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Catalog number
bs-0930R-FITC
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Price
Please ask
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Size
0.1ml
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Long name
HP1(Tyr43) Polyclonal Antibody, FITC Conjugated
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Category
Conjugated Primary Antibodies
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Conjugation
FITC
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
HP1 Tyr43
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Specificity
This is a highly specific antibody against HP1 Tyr43.
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Modification
Phosphorylation
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Modification site
Tyr43
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
KLH conjugated synthetic phosphopeptide derived from Drosophila Melanogaster HP1 around the phosphorylation site of Tyr43
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Gene ID number
34119
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Other Species
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Crossreactive species details
Fruit Fly
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Antigen background
HP1 alpha is a component of heterochromatin. It recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, the chromo shadow domain. Both domains of HP1 are required for binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission
494nm/518nm
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Synonyms
Heterochromatin protein 1; HP1; Non-histone chromosomal protein C1A9 antigen; CG8409
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Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
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Additional conjugation
Anti-FITC Antibody
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French translation
anticorps
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Gene target
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Gene symbol
CBX5, HP1BP3, CBX1, TFF1
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Short name
Anti-HP1 Tyr43
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Technique
Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
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Isotype
Immunoglobulin G (IgG)
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Label
FITC
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Alternative name
Anti-HP1 Tyr43 PAb FITC
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Alternative technique
antibodies, fluorescine
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Gene info
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Identity
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Gene
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Long gene name
chromobox 5
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Synonyms gene name
- chromobox homolog 5 (Drosophila HP1 alpha)
- chromobox homolog 5 (HP1 alpha homolog, Drosophila)
- chromobox homolog 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1999-10-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chromobox family
- MicroRNA protein coding host genes
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
chromobox 1
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Synonyms gene name
- chromobox homolog 1 (Drosophila HP1 beta)
- chromobox homolog 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1999-10-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
trefoil factor 1
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Synonyms gene
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Synonyms gene name
- breast cancer, estrogen-inducible sequence expressed in
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Synonyms
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GenBank acession
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
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Tree numbers
- E01.370.225.500.607.512.240
- E01.370.225.750.551.512.240
- E05.200.500.607.512.240
- E05.200.750.551.512.240
- E05.478.583.375
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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