HB-EGF Antibody, FITC Conjugated

• Catalog number
  bs-3576R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  HB-EGF Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  HB-EGF
• Specificity
  This is a highly specific antibody against HB-EGF.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  90-140/208
• Subcellular location
  Extracellular
• Source
  KLH conjugated synthetic peptide derived from human HB-EGF/DTSF
• Gene ID number
  1839
• Swiss Prot
  Q99075
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  DTR; DTS; DTSF; HEGFL; Proheparin-binding EGF-like growth factor; HBEGF
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  HB-EGF   Conjugated  
• Gene symbol
  EGF, HMHB1, KRT84, HBEGF, KRT85, KRT81, KRT82, KRT83, PEG10
• Short name
  Anti-HB-EGF
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-HB-EGF PAb FITC
• Alternative technique
  antibodies, fluorescine
• Alternative to gene target
  epidermal growth factor, HOMG4 and URG, EGF and IDBG-34100 and ENSG00000138798 and 1950, transmembrane receptor protein tyrosine kinase activator activity, Extracellular, Egf and IDBG-193432 and ENSMUSG00000028017 and 13645

Gene info

• Identity
  HGNC:3229
• Gene
  EGF
• Long gene name
  epidermal growth factor
• Synonyms gene name
  • epidermal growth factor (beta-urogastrone)
• Synonyms name
  • Pro-epidermal growth factor
• GenBank acession
  • X04571
• Locus
  4q25
• Discovery year
  2001-06-22
• Entrez gene record
  1950
• VEGA ID
  OTTHUMG00000132044

Gene info

• Identity
  HGNC:29677
• Gene
  HMHB1
• Long gene name
  histocompatibility minor HB-1
• Synonyms
  • HB-1
  • HB-1Y
• GenBank acession
  • AF103884
• Locus
  5q31.3
• Discovery year
  2006-07-20
• Entrez gene record
  57824
• Pubmed identfication
  • 9892612
• RefSeq identity
  • NM_021182
• Classification
  • Minor histocompatibility antigens
• VEGA ID
  OTTHUMG00000163173

Gene info

• Identity
  HGNC:6461
• Gene
  KRT84
• Long gene name
  keratin 84
• Synonyms gene
  • KRTHB4
• Synonyms gene name
  • keratin, hair, basic, 4
  • keratin 84, type II
• Synonyms
  • Hb-4
• Synonyms name
  • hard keratin type II 4
• GenBank acession
  • Y19209
• Locus
  12q13.13
• Discovery year
  1998-04-21
• Entrez gene record
  3890
• Pubmed identfication
  • 2431943
  • 16831889
• RefSeq identity
  • NM_033045
• Classification
  • Keratins, type II
• VEGA ID
  OTTHUMG00000169634

Gene info

• Identity
  HGNC:3059
• Gene
  HBEGF
• Long gene name
  heparin binding EGF like growth factor
• Synonyms gene
  • HEGFL
  • DTS
  • DTR
• Synonyms gene name
  • diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor)
  • heparin-binding EGF-like growth factor
• Synonyms name
  • Diphtheria toxin receptor (heparin-binding EGF-like growth factor)
  • heparin-binding epidermal growth factor
• Locus
  5q31.3
• Discovery year
  2001-06-22
• Entrez gene record
  1839
• Pubmed identfication
  • 7590736
  • 12163414
• RefSeq identity
  • NM_001945
• VEGA ID
  OTTHUMG00000129496

Gene info

• Identity
  HGNC:6462
• Gene
  KRT85
• Long gene name
  keratin 85
• Synonyms gene
  • KRTHB5
• Synonyms gene name
  • keratin, hair, basic, 5
  • keratin 85, type II
• Synonyms
  • Hb-5
• Synonyms name
  • hard keratin type II
• GenBank acession
  • X99140
• Locus
  12q13.13
• Discovery year
  1998-04-21
• Entrez gene record
  3891
• Pubmed identfication
  • 9084137
  • 16831889
• RefSeq identity
  • NM_002283
• Classification
  • Keratins, type II
• VEGA ID
  OTTHUMG00000169633

Gene info

• Identity
  HGNC:6458
• Gene
  KRT81
• Long gene name
  keratin 81
• Synonyms gene
  • KRTHB1
• Synonyms gene name
  • keratin, hair, basic, 1
  • keratin 81, type II
• Synonyms
  • Hb-1
• Synonyms name
  • hard keratin type II 1
• GenBank acession
  • X81420
• Locus
  12q13.13
• Discovery year
  1998-04-21
• Entrez gene record
  3887
• Pubmed identfication
  • 7556444
  • 16831889
• RefSeq identity
  • NM_002281
• Classification
  • Keratins, type II
• VEGA ID
  OTTHUMG00000167574

Gene info

• Identity
  HGNC:6459
• Gene
  KRT82
• Long gene name
  keratin 82
• Synonyms gene
  • KRTHB2
• Synonyms gene name
  • keratin, hair, basic, 2
  • keratin 82, type II
• Synonyms
  • Hb-2
• Synonyms name
  • hard keratin type II 2
• GenBank acession
  • Y19207
• Locus
  12q13.13
• Discovery year
  1998-04-21
• Entrez gene record
  3888
• Pubmed identfication
  • 2431943
  • 16831889
• RefSeq identity
  • NM_033033
• Classification
  • Keratins, type II
• VEGA ID
  OTTHUMG00000169636

Gene info

• Identity
  HGNC:6460
• Gene
  KRT83
• Long gene name
  keratin 83
• Synonyms gene
  • KRTHB3
• Synonyms gene name
  • keratin, hair, basic, 3
  • keratin 83, type II
• Synonyms
  • Hb-3
• Synonyms name
  • hard keratin type II
• GenBank acession
  • X99141
• Locus
  12q13.13
• Discovery year
  1998-04-21
• Entrez gene record
  3889
• Pubmed identfication
  • 9084137
  • 16831889
• RefSeq identity
  • NM_002282
• Classification
  • Keratins, type II
• VEGA ID
  OTTHUMG00000169632
• Locus Specific Databases
  • LRG_1302

Gene info

• Identity
  HGNC:14005
• Gene
  PEG10
• Long gene name
  paternally expressed 10
• Synonyms
  • KIAA1051
  • HB-1
  • MEF3L
  • RGAG3
  • Mar2
  • Mart2
  • SIRH1
  • RTL2
• Synonyms name
  • Sushi-Ichi retrotransposon homolog 1
  • mammalian retrotransposon-derived 2
  • retrotransposon Gag like 2
• GenBank acession
  • AB049834
• Locus
  7q21.3
• Discovery year
  2000-11-28
• Entrez gene record
  23089
• Pubmed identfication
  • 11318613
  • 15716091
  • 16093683
• RefSeq identity
  • NM_015068
• Classification
  • Retrotransposon Gag like
• VEGA ID
  OTTHUMG00000155578
• Locus Specific Databases
  • LRG_1097

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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