GRM2+GRM4 Antibody, Cy5.5 Conjugated

• Catalog number
  bs-2139R-Cy5.5
• Price
  Please ask
• Size
  0.1ml

• Long name
  GRM2+GRM4 Polyclonal Antibody, Cy5.5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5.5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  GRM2+GRM4
• Specificity
  This is a highly specific antibody against GRM2+GRM4.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human GRM2+GRM4
• Gene ID number
  2912
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  675nm/694nm
• Synonyms
  NULL
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5, Cy5.5
• Conjugated
  These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
• French translation
  anticorps

• Gene target
  GRM2+GRM4   Conjugated  
• Gene symbol
  GRM2, GRM4
• Short name
  Anti-GRM2+GRM4
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5.5
• Alternative name
  Anti-GRM2+GRM4 PAb Cy5.5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4594
• Gene
  GRM2
• Long gene name
  glutamate metabotropic receptor 2
• Synonyms gene name
  • glutamate receptor, metabotropic 2
• Synonyms
  • GPRC1B
  • mGlu2
  • MGLUR2
• GenBank acession
  • L35318
• Locus
  3p21.2
• Discovery year
  1993-10-21
• Entrez gene record
  2912
• Pubmed identfication
  • 7620613
• Classification
  • Glutamate metabotropic receptors
• VEGA ID
  OTTHUMG00000156902

Gene info

• Identity
  HGNC:4596
• Gene
  GRM4
• Long gene name
  glutamate metabotropic receptor 4
• Synonyms gene name
  • glutamate receptor, metabotropic 4
• Synonyms
  • GPRC1D
  • mGlu4
  • MGLUR4
• GenBank acession
  • U92457
• Locus
  6p21.31
• Discovery year
  1993-10-21
• Entrez gene record
  2914
• Pubmed identfication
  • 8738157
  • 9473604
• Classification
  • Glutamate metabotropic receptors
• VEGA ID
  OTTHUMG00000014538

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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