GPR44 Antibody, Biotin Conjugated

• Catalog number
  bs-13537R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  GPR44 Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  GPR44
• Specificity
  This is a highly specific antibody against GPR44.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  169-210/395
• Subcellular location
  Extracellular
• Source
  KLH conjugated synthetic peptide derived from human GPR44/CD294
• Gene ID number
  11251
• Swiss Prot
  Q9Y5Y4
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  DP2; DL1R; CD294; CRTH2; GPR44; Prostaglandin D2 receptor 2; Chemoattractant receptor-homologous molecule expressed on Th2 cells; G-protein coupled receptor 44; PTGDR2
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  GPR44   Conjugated  
• Gene symbol
  PTGDR2
• Short name
  Anti-GPR44
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-GPR44 PAb Biotin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4502
• Gene
  PTGDR2
• Long gene name
  prostaglandin D2 receptor 2
• Synonyms gene
  • GPR44
• Synonyms gene name
  • G protein-coupled receptor 44
• Synonyms
  • CRTH2
  • CD294
  • DP2
• Synonyms name
  • chemoattractant receptor homologous molecule expressed on T helper type 2 cells
• GenBank acession
  • AF118265
• Locus
  11q12.2
• Discovery year
  1999-03-12
• Entrez gene record
  11251
• Pubmed identfication
  • 10036181
• RefSeq identity
  • NM_004778
• Classification
  • CD molecules
  • Prostaglandin receptors
• VEGA ID
  OTTHUMG00000167796

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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