GATA3 (Ser162) Antibody, Cy5.5 Conjugated

• Catalog number
  bs-10280R-Cy5.5
• Price
  Please ask
• Size
  0.1ml

• Long name
  GATA3 (Ser162) Polyclonal Antibody, Cy5.5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5.5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  GATA3 Ser162
• Specificity
  This is a highly specific antibody against GATA3 Ser162.
• Modification
  Phosphorylation
• Modification site
  Ser162
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular, Helical
• Source
  KLH conjugated synthetic phosphopeptide derived from human GATA3 around the phosphorylation site of Ser162
• Gene ID number
  2625
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary; lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  675nm/694nm
• Synonyms
  GATA3 phospho S162; p-GATA3 phospho S162; GATA3 phospho Ser162; p-GATA3 Ser162; GATA 3; GATA3; GATA-3; GATA binding factor 3; GATA binding protein 3; HDR; MGC2346; MGC5199; MGC5445; Trans acting T cell specic transcription factor GATA 3; GATA3_HUMAN; Trans-acting T-cell-specic transcription factor GATA-3; GATA-binding factor 3.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5, Cy5.5
• Conjugated
  These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
• French translation
  anticorps

• Gene target
  GATA3   Ser162   Conjugated  
• Gene symbol
  GATA3, GATA3-AS1
• Short name
  Anti-GATA3 Ser162
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5.5
• Alternative name
  Anti-GATA3 Ser162 PAb Cy5.5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4172
• Gene
  GATA3
• Long gene name
  GATA binding protein 3
• Synonyms gene name
  • GATA-binding protein 3
• Synonyms
  • HDR
• GenBank acession
  • X55122
• Locus
  10p14
• Discovery year
  1992-11-03
• Entrez gene record
  2625
• Pubmed identfication
  • 2050118
  • 15087456
• RefSeq identity
  • NM_001002295
• Classification
  • GATA zinc finger domain containing
• VEGA ID
  OTTHUMG00000017640

Gene info

• Identity
  HGNC:33786
• Gene
  GATA3-AS1
• Long gene name
  GATA3 antisense RNA 1
• GenBank acession
  • BC036297
  • AK128810
• Locus
  10p14
• Discovery year
  2012-12-04
• Entrez gene record
  399717
• Pubmed identfication
  • 23870669
  • 30420860
• RefSeq identity
  • NR_104327
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000156966

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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