GATA2 (Ser401) Antibody, FITC Conjugated

• Catalog number
  bs-13293R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  GATA2 (Ser401) Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  GATA2 Ser401
• Specificity
  This is a highly specific antibody against GATA2 Ser401.
• Modification
  Phosphorylation
• Modification site
  Ser401
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human GATA2 around the phosphorylation site of Ser401
• Gene ID number
  2624
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary; lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  GATA2 phospho S401; p-GATA2 phospho S401; GATA-2; GATA 2; GATA Binding Protein 2; GATA-binding protein 2; Gata2; GATA2_HUMAN; MGC2306; NFE 1B; NFE1B.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  GATA2   Ser401   Conjugated  
• Gene symbol
  GATA2, GATA2-AS1
• Short name
  Anti-GATA2 Ser401
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-GATA2 Ser401 PAb FITC
• Alternative technique
  antibodies, fluorescine
• Alternative to gene target
  GATA binding protein 2, DCML and IMD21 and MONOMAC and NFE1B, GATA2 and IDBG-55213 and ENSG00000179348 and 2624, C2H2 zinc finger domain binding, nuclei, Gata2 and IDBG-166776 and ENSMUSG00000015053 and 14461, GATA2 and IDBG-646502 and ENSBTAG00000019707 and 506809

Gene info

• Identity
  HGNC:4171
• Gene
  GATA2
• Long gene name
  GATA binding protein 2
• Synonyms gene name
  • GATA-binding protein 2
• Synonyms
  • NFE1B
• GenBank acession
  • AF169253
• Locus
  3q21.3
• Discovery year
  1992-11-03
• Entrez gene record
  2624
• Pubmed identfication
  • 1714909
• RefSeq identity
  • NM_032638
• Classification
  • GATA zinc finger domain containing
• VEGA ID
  OTTHUMG00000159689
• Locus Specific Databases
  • LRG_295

Gene info

• Identity
  HGNC:51108
• Gene
  GATA2-AS1
• Long gene name
  GATA2 antisense RNA 1
• Locus
  3q21.3
• Discovery year
  2014-07-29
• Entrez gene record
  101927167
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000159693

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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