Gastrin receptor/CCKBR Antibody, HRP Conjugated

• Catalog number
  bs-1777R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  Gastrin receptor/CCKBR Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Gastrin receptor/GASR/CCKBR
• Specificity
  This is a highly specific antibody against Gastrin receptor/GASR/CCKBR.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  300-350/447
• Subcellular location
  Cytoplasm
• Source
  KLH conjugated synthetic peptide derived from human Gastrin receptor
• Gene ID number
  887
• Swiss Prot
  P32239
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  GASR; CCK-B; CCK2R; Gastrin/cholecystokinin type B receptor; CCK-B receptor; CCK-BR; Cholecystokinin-2 receptor; CCK2-R; CCKBR; CCKRB
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  Gastrin   receptor/CCKBR   Conjugated  
• Gene symbol
  CCKBR
• Short name
  Anti-Gastrin receptor/GASR/CCKBR
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-Gastrin receptor/GASR/CCKBR PAb HRP
• Alternative technique
  antibodies
• Alternative to gene target
  cholecystokinin B receptor, CCK-B and CCK2R and GASR, CCKBR and IDBG-28586 and ENSG00000110148 and 887, 1-phosphatidylinositol-3-kinase regulator activity, Plasma membranes, Cckbr and IDBG-204676 and ENSMUSG00000030898 and 12426, CCKBR and IDBG-634214 and ENSBTAG00000005236 and 281665

Gene info

• Identity
  HGNC:1571
• Gene
  CCKBR
• Long gene name
  cholecystokinin B receptor
• GenBank acession
  • D13305
• Locus
  11p15.4
• Discovery year
  1993-07-13
• Entrez gene record
  887
• Pubmed identfication
  • 1280419
• RefSeq identity
  • NM_176875
• Classification
  • Cholecystokinin receptors
• VEGA ID
  OTTHUMG00000133380

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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