FMR2/AFF2 Antibody, Cy7 Conjugated

• Catalog number
  bs-11703R-Cy7
• Price
  Please ask
• Size
  0.1ml

• Long name
  FMR2/AFF2 Antibody, Cy7 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy7
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  FMR2/AFF2
• Specificity
  This is a highly specific antibody against FMR2/AFF2.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human AFF2
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  FMR2 is a 1311 amino acid nuclear protein belonging to the AF4 family. Expressed in the brain, placenta and lung, FMR2 exists as two isoforms produced by alternative splicing. Defects in the gene that encodes FMR2 have been found to be a cause of FRAXE, an X-linked form of mental retardation. Individuals expressing the FRAXE site also have more than two-hundred copies of a GCC repeat adjacent to CpG island, compared to six to thirty-five copies of the GCC repeat in a normal individual. It is believed that loss of FMR2 expression causes this GCC expansion of the FRAXE site.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  743nm/767nm
• Synonyms
  AF4/FMR2 family member 2; AF4/FMR2 family, member 2; AFF2; AFF2_HUMAN; FMR2; FMR2P; Fragile X E mental retardation syndrome protein; fragile X mental retardation 2; Fragile X mental retardation 2 protein; fragile X mental retardation gene associated with FRAXE; FRAXE; mild or borderline mental retardation; MRX2; OX19; Protein FMR-2; Protein Ox19.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugated
  These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
• Additional conjugation
  Cy7
• French translation
  anticorps

• Gene target
  FMR2/AFF2   Conjugated  
• Gene symbol
  AFF2, AFF2-IT1
• Short name
  Anti-FMR2/AFF2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy7
• Alternative name
  Anti-FMR2/AFF2 PAb Cy7
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3776
• Gene
  AFF2
• Long gene name
  AF4/FMR2 family member 2
• Synonyms gene
  • FMR2
• Synonyms gene name
  • fragile X mental retardation 2
  • AF4/FMR2 family, member 2
• Synonyms
  • FRAXE
• GenBank acession
  • U48436
• Locus
  Xq28
• Discovery year
  2005-06-27
• Entrez gene record
  2334
• Pubmed identfication
  • 22065534
• RefSeq identity
  • NM_002025
• Classification
  • AF4/FMR2 family
  • Super elongation complex
• VEGA ID
  OTTHUMG00000022613
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:41334
• Gene
  AFF2-IT1
• Long gene name
  AFF2 intronic transcript 1
• Synonyms gene name
  • AFF2 intronic transcript 1 (non-protein coding)
• Locus
  Xq28
• Discovery year
  2011-05-20
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000022611

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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