FISH Antibody, Cy5 Conjugated

• Catalog number
  bs-11645R-Cy5
• Price
  Please ask
• Size
  0.1ml

• Long name
  FISH Polyclonal Antibody, Cy5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  FISH
• Specificity
  This is a highly specific antibody against FISH.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human FISH
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Fish, a potential Src substrate, is a broadly expressed adaptor protein containing five SH3 domains and a phox homology (PX) domain (1). The Src family of protein tyrosine kinases act in signal transduction pathways (2-4). Src kinases vary in expression but are strongly regulated in vivo; catalytic activity is repressed by interacting with the SH3 domain (5-7). In Src-transformed fibroblasts and in normal cells treated with certain growth factors fish is tyrosine-phosphorylated (1). Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish, along with activation of Src (1). Fish is likely to be involved in tyrosine kinase signaling and may have a role in cytoskeletal changes (1).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  625,650nm/670nm
• Synonyms
  Adapter protein TKS5; Five SH3 domain-containing protein; SH3 and PX domain-containing protein 2A; SH3 multiple domains protein 1; Sh3md1; Sh3pxd2a; SPD2A_HUMAN; TKs5; Tyrosine kinase substrate with five SH3 domains.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5
• French translation
  anticorps

• Gene target
  FISH   Conjugated  
• Gene symbol
  SH3PXD2A
• Short name
  Anti-FISH
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5
• Species
  Fish, Fishes
• Alternative name
  Anti-FISH PAb Cy5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:23664
• Gene
  SH3PXD2A
• Long gene name
  SH3 and PX domains 2A
• Synonyms gene
  • SH3MD1
• Synonyms gene name
  • SH3 multiple domains 1
• Synonyms
  • FISH
  • KIAA0418
• Synonyms name
  • five SH3 domains
• GenBank acession
  • AB007878
• Locus
  10q24.33
• Discovery year
  2003-12-01
• Entrez gene record
  9644
• Pubmed identfication
  • 9687503
• RefSeq identity
  • NM_014631
• VEGA ID
  OTTHUMG00000018997

MeSH Data

• Name
  In Situ Hybridization, Fluorescence
• Concept
  Scope note: A type of IN SITU HYBRIDIZATION in which target sequences are stained with fluorescent dye so their location and size can be determined using fluorescence microscopy. This staining is sufficiently distinct that the hybridization signal can be seen both in metaphase spreads and in interphase nuclei.
• Tree numbers
  • E01.370.225.500.620.670.325.350
  • E01.370.225.750.600.670.325.350
  • E05.200.500.620.670.325.350
  • E05.200.750.600.670.325.350
  • E05.393.285.350
  • E05.393.661.475.350
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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