FIG4/SAC3 Antibody, Cy3 Conjugated

• Catalog number
  bs-11690R-Cy3
• Price
  Please ask
• Size
  0.1ml

• Long name
  FIG4/SAC3 Polyclonal Antibody, Cy3 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy3
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  FIG4/SAC3
• Specificity
  This is a highly specific antibody against FIG4/SAC3.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human FIG4
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  FIG4 is a 907 amino acid protein that contains one SAC domain through which it is thought to function as a phosphoinositide phosphatase that may play an important role in signal transduction and vesicle trafficking. Defects in the gene encoding FIG4 are the cause of Charcot-Marie-Tooth disease type 4J (CMT4J) and amyotrophic lateral sclerosis type 11 (ALS11), both of which negatively affect the nervous system. CMT4J is a recessive demyelinating disorder of the peripheral nervous system and is characterized by reduced motor nerve conduction velocities and axonal degeneration. Unlike CMT4J, ALS11 is characterized by the degeneration of upper motor neurons in the brain and lower neurons in the spinal cord, causing paralysis and, ultimately, death.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  512,550nm/570,615nm
• Synonyms
  5-bisphosphate 5-phosphatase; Fig4; FIG4_HUMAN; KIAA0274; ALS11; Phosphatidylinositol 3; hSac3; Phosphatidylinositol 3,5 bisphosphate 5 phosphatase; Polyphosphoinositide phosphatase; SAC domain containing protein 3; SAC domain-containing protein 3; SAC3.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the Anti-FIG4/SAC3 can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy.
• Additional conjugation
  cy3 conjugation kit
• French translation
  anticorps

• Gene target
  FIG4/SAC3   Conjugated  
• Gene symbol
  FIG4, MCM3AP
• Short name
  Anti-FIG4/SAC3
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy3
• Alternative name
  Anti-FIG4/SAC3 PAb Cy3
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16873
• Gene
  FIG4
• Long gene name
  FIG4 phosphoinositide 5-phosphatase
• Synonyms gene
  • KIAA0274
• Synonyms gene name
  • KIAA0274
  • FIG4 homolog (S. cerevisiae)
  • FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
• Synonyms
  • SAC3
  • hSac3
  • dJ249I4.1
  • ALS11
  • CMT4J
• GenBank acession
  • D87464
• Locus
  6q21
• Discovery year
  2003-11-26
• Entrez gene record
  9896
• Pubmed identfication
  • 9039502
  • 11274189
  • 17572665
• RefSeq identity
  • NM_014845
• Classification
  • Phosphoinositide phosphatases
• VEGA ID
  OTTHUMG00000015352
• Locus Specific Databases
  • LRG_241

Gene info

• Identity
  HGNC:6946
• Gene
  MCM3AP
• Long gene name
  minichromosome maintenance complex component 3 associated protein
• Synonyms gene name
  • minichromosome maintenance deficient (S. cerevisiae) 3-associated protein
  • MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) associated protein
• Synonyms
  • Map80
  • KIAA0572
  • GANP
  • SAC3
• Synonyms name
  • germinal-centre associated nuclear protein
• GenBank acession
  • AB005543
• Locus
  21q22.3
• Discovery year
  1999-03-04
• Entrez gene record
  8888
• Pubmed identfication
  • 9712829
  • 16914116
  • 21195085
• RefSeq identity
  • NM_003906
• Classification
  • Lysine acetyltransferases
  • Transcription and export complex 2
• VEGA ID
  OTTHUMG00000090630

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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