FAK(Ser910) Antibody, HRP Conjugated

• Catalog number
  bs-13133R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  FAK(Ser910) Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  FAK Ser910
• Specificity
  This is a highly specific antibody against FAK Ser910.
• Modification
  Phosphorylation
• Modification site
  Ser910
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human PTK2 around the phosphorylation site of Tyr910
• Gene ID number
  5747
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  FAK phospho S910; p-FAK phospho S910; FADK 1; FADK; FAK 1; FAK related non kinase polypeptide; FAK1; Focal adhesion kinase 1; FRNK; pp125FAK; Protein tyrosine kinase 2; Protein Tyrosine Kinase Cytoplasmic; PTK 2; FAK1_HUMAN; Focal adhesion kinase-related nonkinase; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  FAK   Ser910   Conjugated  
• Gene symbol
  PTK2
• Short name
  Anti-FAK Ser910
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-FAK Ser910 PAb HRP
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9611
• Gene
  PTK2
• Long gene name
  protein tyrosine kinase 2
• Synonyms gene name
  • PTK2 protein tyrosine kinase 2
• Synonyms
  • FAK
  • FADK
  • FAK1
  • PPP1R71
• Synonyms name
  • protein phosphatase 1, regulatory subunit 71
• GenBank acession
  • L13616
• Locus
  8q24.3
• Discovery year
  1992-10-02
• Entrez gene record
  5747
• Pubmed identfication
  • 8422239
• RefSeq identity
  • NM_005607
• Classification
  • Protein phosphatase 1 regulatory subunits
  • FERM domain containing
  • PTK2 family tyrosine kinases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000067438

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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