EZH2 (Thr487) Antibody, FITC Conjugated

• Catalog number
  bs-6529R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  EZH2 (Thr487) Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  EZH2 Thr487
• Specificity
  This is a highly specific antibody against EZH2 Thr487.
• Modification
  Phosphorylation
• Modification site
  Thr487
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human KMT6 around the phosphorylation site of Thr487 [VD(p-T)P]
• Gene ID number
  2146
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  KMT6/EZH2phospho T487; KMT6/EZH2phospho Thr487; p-KMT6/EZH2phospho T487; p-KMT6/EZH2Thr487; p-KMT6/EZH2T487; Enhancer of zeste homolog 2; Enx1h; MGC9169; Enhancer of zeste 2; ENX-1; ENX 1; ENX1; EZH1; EZH2; EZH 2; EZH2_HUMAN; Histone-lysine N-methyltransferase EZH2; KMT6A; Lysine N-methyltransferase 6; Enhancer of zeste homolog 2 Drosophila; Enhancer of zeste, Drosophila, homolog 2; KMT 6; KMT6; KMT6A; WVS2.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  EZH2   Thr487   Conjugated  
• Gene symbol
  EZH2
• Short name
  Anti-EZH2 Thr487
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-EZH2 Thr487 PAb FITC
• Alternative technique
  antibodies, fluorescine

Gene info

• Identity
  HGNC:3527
• Gene
  EZH2
• Long gene name
  enhancer of zeste 2 polycomb repressive complex 2 subunit
• Synonyms gene name
  • enhancer of zeste (Drosophila) homolog 2
  • enhancer of zeste homolog 2 (Drosophila)
• Synonyms
  • EZH1
  • ENX-1
  • KMT6
  • KMT6A
• Locus
  7q36.1
• Discovery year
  1995-12-21
• Entrez gene record
  2146
• Pubmed identfication
  • 8954776
  • 17172412
• RefSeq identity
  • NM_004456
• Classification
  • SET domain containing
  • Polycomb repressive complex 2
  • Lysine methyltransferases
  • Myb/SANT domain containing
• VEGA ID
  OTTHUMG00000158973
• Locus Specific Databases
  • LRG_531

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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