EMP1 Antibody, Cy5 Conjugated

• Catalog number
  bs-0558R-Cy5
• Price
  Please ask
• Size
  0.1ml

• Long name
  EMP1 Polyclonal Antibody, Cy5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  EMP1
• Specificity
  This is a highly specific antibody against EMP1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  105-135/160
• Subcellular location
  Cell membrane
• Source
  KLH conjugated synthetic peptide derived from mouse Emp1
• Gene ID number
  13730
• Swiss Prot
  P47801
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion. When EMP-1 is overexpressed, cell proliferation is inhibited, S phase is arrested and G1 phase is prolonged in esophogeal cancer cells. EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  625,650nm/670nm
• Synonyms
  TMP; I-8-9; Epithelial membrane protein 1; EMP-1; Tumor-associated membrane protein; Emp1
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5
• French translation
  anticorps

• Gene target
  EMP1   Conjugated  
• Gene symbol
  EMP1
• Short name
  Anti-EMP1
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5
• Alternative name
  Anti-EMP1 PAb Cy5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3333
• Gene
  EMP1
• Long gene name
  epithelial membrane protein 1
• Synonyms
  • TMP
  • CL-20
• GenBank acession
  • U43916
• Locus
  12p13.1
• Discovery year
  1997-12-05
• Entrez gene record
  2012
• Pubmed identfication
  • 8996089
  • 9126480
• RefSeq identity
  • NM_001423
• VEGA ID
  OTTHUMG00000168775

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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