DR3 Antibody, Biotin Conjugated

• Catalog number
  bs-0421R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  DR3 Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  DR3
• Specificity
  This is a highly specific antibody against DR3.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  370-417/417
• Subcellular location
  Cell membrane, Intracellular
• Source
  KLH conjugated synthetic peptide derived from human DR3
• Gene ID number
  8718
• Swiss Prot
  Q93038
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; WSL-LR; TNFRSF12; Tumor necrosis factor receptor superfamily member 25; Apoptosis-inducing receptor AIR; Apoptosis-mediating receptor DR3; Apoptosis-mediating receptor TRAMP; Death receptor 3; Lymphocyte-associated receptor of death; Protein WSL; Protein WSL-1; TNFRSF25; APO3; WSL; WSL1; UNQ455/PRO779
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  DR3   Conjugated  
• Gene symbol
  TNFRSF25
• Short name
  Anti-DR3
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-DR3 PAb Biotin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11910
• Gene
  TNFRSF25
• Long gene name
  TNF receptor superfamily member 25
• Synonyms gene
  • TNFRSF12
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)
  • tumor necrosis factor receptor superfamily, member 25
• Synonyms
  • DR3
  • TRAMP
  • WSL-1
  • LARD
  • WSL-LR
  • DDR3
  • TR3
  • APO-3
• GenBank acession
  • U72763
• Locus
  1p36.31
• Discovery year
  1998-12-04
• Entrez gene record
  8718
• Pubmed identfication
  • 9052839
  • 8934525
• RefSeq identity
  • NM_148965
• Classification
  • Tumor necrosis factor receptor superfamily
• VEGA ID
  OTTHUMG00000000831

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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