DNA Polymerase Kappa/POLK Antibody, Cy3 Conjugated
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Catalog numberbs-13019R-Cy3
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PricePlease ask
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Size0.1ml
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Long nameDNA Polymerase Kappa/POLK Antibody, Cy3 Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationCy3
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenDNA Polymerase Kappa/POLK
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SpecificityThis is a highly specific antibody against DNA Polymerase Kappa/POLK.
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ModificationUnmodified
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Modification siteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic peptide derived from human DNA Polymerase Kappa/POLK
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Gene ID number51426
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen backgroundDNA polymerase lambda (pol Kappa), also designated DNA polymerase Kappa or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol Kappa is a member of the DNA polymerase type-X family. Pol Kappa extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol Kappa may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol Kappa and thus influences the ability of pol Kappa to synthesize DNA.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission512,550nm/570,615nm
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SynonymsDNA polymerase kappa; DINB protein; Short=DINP; POLK_HUMAN.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser. 1 of the Anti-DNA Polymerase Kappa/POLK can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC. This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy.
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Additional conjugationcy3 conjugation kit
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French translationanticorps
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Gene target
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Gene symbolPOLK, PRKDC, TENT4A, HLA-DOA
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Short nameAnti-DNA Polymerase Kappa/POLK
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TechniqueAntibody, dna, antibodies against human proteins, antibodies for, antibody Conjugates
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IsotypeImmunoglobulin G (IgG)
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LabelCy3
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Alternative nameAnti-DNA Polymerase Kappa/POLK PAb Cy3
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameDNA polymerase kappa
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Synonyms gene
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Synonyms gene name
- polymerase (DNA directed) kappa
- polymerase (DNA) kappa
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-08-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- DNA polymerases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprotein kinase, DNA-activated, catalytic subunit
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Synonyms gene
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Synonyms gene name
- protein kinase, DNA-activated, catalytic polypeptide
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Synonyms
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Synonyms name
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Locus
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Discovery year1993-11-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Armadillo like helical domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameterminal nucleotidyltransferase 4A
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Synonyms gene
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Synonyms gene name
- polymerase (DNA directed) sigma
- PAP associated domain containing 7
- poly(A) RNA polymerase D7, non-canonical
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-09-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Terminal nucleotidyltransferases
- Non-canonical poly(A) polymerases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class II, DO alpha
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C1-set domain containing
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data