DIRC2 Antibody, HRP Conjugated

• Catalog number
  bs-8278R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  DIRC2 Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  DIRC2
• Specificity
  This is a highly specific antibody against DIRC2.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human DIRC2
• Gene ID number
  84925
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Belonging to the major facilitator superfamily, DIRC2 (disrupted in renal carcinoma protein 2) is a 478 amino acid multi-pass membrane protein that is primarily expressed in kidney proximal tubular cells. The genes encoding DIRC2 and DIRC3 are located at a translocation breakpoint which occurs frequently in individuals affected by familial renal cell carcinoma. Fusion transcripts that result from these translocations may affect normal protein function. This evidence suggests that, due to its chromosomal location, deregulation of the DIRC2 gene may cause haploinsufficiency and therefore result in the onset of tumor growth. There are two isoforms of DIRC2 which are produced as a result of alternative splicing events.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  Disrupted in renal carcinoma protein 2; DIRC 2; Disrupted in renal cancer protein 2; Disrupted in renal carcinoma 2; FLJ14784; NP_116228; RCC 4; RCC4; Renal cell carcinoma 4; DIRC2_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  DIRC2   Conjugated  
• Gene symbol
  SLC49A4
• Short name
  Anti-DIRC2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-DIRC2 PAb HRP
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16628
• Gene
  SLC49A4
• Long gene name
  solute carrier family 49 member 4
• Synonyms gene
  • DIRC2
• Synonyms gene name
  • disrupted in renal carcinoma 2
• Synonyms
  • FLJ14784
  • RCC4
• Synonyms name
  • renal cell carcinoma 4
  • disrupted in renal cancer protein 2
• GenBank acession
  • AK027690
• Locus
  3q21.1
• Discovery year
  2002-03-19
• Entrez gene record
  84925
• Pubmed identfication
  • 11912179
• RefSeq identity
  • NM_032839
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000159553

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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