CYP8A1/PTGIS Antibody, FITC Conjugated

• Catalog number
  bs-3677R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  CYP8A1/PTGIS Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CYP8A1/PTGIS
• Specificity
  This is a highly specific antibody against CYP8A1/PTGIS.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human CYP8A1/PTGIS
• Gene ID number
  5740
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  CYP8; CYP8A1; Cytochrome P450, family 8, subfamily A, polypeptide 1; PGIS; Prostacyclin synthase; Prostaglandin I2 prostacyclin synthase; Prostaglandin I2 synthase; PTGI.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  CYP8A1/PTGIS   Conjugated  
• Gene symbol
  PTGIS
• Short name
  Anti-CYP8A1/PTGIS
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-CYP8A1/PTGIS PAb FITC
• Alternative technique
  antibodies, fluorescine
• Alternative to gene target
  prostaglandin I2 (prostacyclin) synthase, CYP8 and CYP8A1 and PGIS and PTGI, PTGIS and IDBG-80513 and ENSG00000124212 and 5740, oxidoreductase activity, nuclei, Ptgis and IDBG-213024 and ENSMUSG00000017969 and 19223, PTGIS and IDBG-643178 and ENSBTAG00000017537 and 101910090,282021

Gene info

• Identity
  HGNC:9603
• Gene
  PTGIS
• Long gene name
  prostaglandin I2 synthase
• Synonyms gene name
  • prostaglandin I2 (prostacyclin) synthase
• Synonyms
  • PGIS
  • CYP8A1
• Synonyms name
  • cytochrome P450, family 8, subfamily A, polypeptide 1
  • prostacyclin synthase
• Locus
  20q13.13
• Discovery year
  1994-07-28
• Entrez gene record
  5740
• Pubmed identfication
  • 8812456
• Classification
  • Cytochrome P450 family 8
• VEGA ID
  OTTHUMG00000033077
• Locus Specific Databases
  • PharmVar Human Cytochrome P450 (CYP) Allele Nomenclature

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products