CYP26A1 Antibody, HRP Conjugated

• Catalog number
  bs-12928R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  CYP26A1 Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CYP26A1
• Specificity
  This is a highly specific antibody against CYP26A1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human CYP26A1
• Gene ID number
  1592
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP26A1 is a major retinoic acid catabolic enzyme. CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid. CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptor ∫2. Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, imperforate anus, agenesis of the caudal portions of the digestive and urogenital tracts, and malformed lumbosacral skeletal elements. CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, human FAP adenomas, human sporadic colon carcinomas, and in the intestine of adenomatous polyposis coli (apcmcr) mutant zebrafish embryos.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  CP26; CP26A_HUMAN; CYP26; CYP26A 1; cyp26a1; Cytochrome P450 26A1; Cytochrome P450 family 26 subfamily A polypeptide 1; Cytochrome P450 retinoic acid-inactivating 1; cytochrome P450, family 26, subfamily A, polypeptide 1; cytochrome P450, subfamily XXVIA, polypeptide 1; Cytochrome P450RAI; hP450RAI; OTTHUMP00000020102; OTTHUMP00000020103; P450; P450 retinoic acid inactivating 1; P450RAI; P450RAI1; Retinoic acid 4 hydroxylase; Retinoic acid 4-hydroxylase; Retinoic acid metabolizing cytochrome; Retinoic acid-metabolizing cytochrome.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  CYP26A1   Conjugated  
• Gene symbol
  CYP26A1
• Short name
  Anti-CYP26A1
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-CYP26A1 PAb HRP
• Alternative technique
  antibodies
• Alternative to gene target
  cytochrome P450, family 26, subfamily A, polypeptide 1, CP26 and CYP26 and P450RAI and P450RAI1, CYP26A1 and IDBG-82645 and ENSG00000095596 and 1592, oxidoreductase activity, Cytoplasm, Cyp26a1 and IDBG-162003 and ENSMUSG00000024987 and 13082, CYP26A1 and IDBG-637647 and ENSBTAG00000021118 and 539047

Gene info

• Identity
  HGNC:2603
• Gene
  CYP26A1
• Long gene name
  cytochrome P450 family 26 subfamily A member 1
• Synonyms gene name
  • cytochrome P450, subfamily XXVIA, polypeptide 1
  • cytochrome P450, family 26, subfamily A, polypeptide 1
• Synonyms
  • P450RAI
  • CP26
  • CYP26
  • P450RAI1
• GenBank acession
  • AF005418
• Locus
  10q23.33
• Discovery year
  1996-12-12
• Entrez gene record
  1592
• Pubmed identfication
  • 9228017
  • 9521883
• Classification
  • Cytochrome P450 family 26
• VEGA ID
  OTTHUMG00000018765
• Locus Specific Databases
  • PharmVar Human Cytochrome P450 (CYP) Allele Nomenclature

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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